Results 141 to 150 of about 19,999 (256)

A systematic review comparing the performance of alternative blackfly (Simulium) trapping methods against the standard human landing catch (HLC) for onchocerciasis surveillance. [PDF]

PLoS Negl Trop Dis
Kyomuhangi I, Mustafa A, Hawkes FM.
europepmc   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Self-efficacy and knowledge trial to improve sexual reproductive health and well-being for Syrian refugee women and girls in Lebanon: a study protocol for a randomized community-based trial. [PDF]

Front Glob Womens Health
Kobeissi L, Ibrahim S, Abdul Sater Z, Bosqui T, Honein-AbouHaidar G, Farhat T, Mohammad Fouad MF, Naal H, Hudroj L, Sarieddine D, Govender V, Say L, Hamadeh R, Saleh S.   +13 more
europepmc   +1 more source

Collectors of Collections: Sherlock Holmes and Collecting Culture [PDF]

Victorians Institute Journal, 2016
openaire   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Prevalence and Associated Factors of Diarrhea Among Under-Five Children in Maraki Health Center, Gondar Zone, Amhara Region, Ethiopia: A Cross-Sectional Study. [PDF]

Health Sci Rep
Dagnaw M, Indracanti M.
europepmc   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Post-Traumatic Lymphatic Vessel Thrombosis Treated With Thrombus Removal and Lymphaticovenous Anastomosis: A Case Report. [PDF]

Microsurgery
Meroni M, Scaglioni MF.
europepmc   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Insect education and outreach: integrating traditional and non-lethal collection techniques. [PDF]

J Insect Sci
Au MG, Adhikari A, Alsdorf AM, Arey NC, Brown HJ, Cohen AL, Elgar SA, Fausett E, Fomekong-Lontchi J, Green T, Jocson DM, Naharki K, Peterson K, White K.   +13 more
europepmc   +1 more source