Results 151 to 160 of about 23,156 (294)

A systematic review comparing the performance of alternative blackfly (Simulium) trapping methods against the standard human landing catch (HLC) for onchocerciasis surveillance. [PDF]

PLoS Negl Trop Dis
Kyomuhangi I, Mustafa A, Hawkes FM.
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Advanced Primary Lymphedema Treated With Duo-Plane Lymphovenous Bypass. [PDF]

Plast Reconstr Surg Glob Open
Zhang M, Liu H, Guo L, Shi Y, Tian L, Dong R, Yu N, Huang J, Long X.   +8 more
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Everyone needs a rock collecting items from nature in childhood

, 2013
Little is known about children’s nature collecting behavior. This study examined the extent of childhood collecting of natural items, the types of items collected, gender differences in items collected, and comparisons between collectors and non ...
Lekies, Kristi S.,, Beery, Thomas,
core  

Insect education and outreach: integrating traditional and non-lethal collection techniques. [PDF]

J Insect Sci
Au MG, Adhikari A, Alsdorf AM, Arey NC, Brown HJ, Cohen AL, Elgar SA, Fausett E, Fomekong-Lontchi J, Green T, Jocson DM, Naharki K, Peterson K, White K.   +13 more
europepmc   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

English folk music on the margin - Cecil Sharp's gypsies

, 2011
Cecil Sharp is the only English or even British collector who can be compared with such European giants as Bela Bartok and Zoltan Kodaly, compsers and collectors who undertook extnsive fieldwork documenting the folk music of indigenous cultures including
Staelens, Yvette
core  

Insights into the seroprevalence of <i>Toxocara</i> spp. in Kuwait: A comparison between the general population and waste collectors. [PDF]

One Health
Yousef A, Alkhamis MA, Daalah M, Al-Awadhi M.   +3 more
europepmc   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source