Results 151 to 160 of about 19,999 (256)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Alexandra Bounia, The Nature of Classical Collecting: Collectors and Collections 100BCE - 100CE

Museum & Society, 2005
Peter Davis
doaj  

Inflammatory Signal Persistence in Pain: Lymphatic Regulation and Neuroimmune Integration. [PDF]

Biology (Basel)
Solari E, Marcozzi C, Vellani V, Pignatelli A, Moriondo A.   +4 more
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Assessment of parental involvement in child health services for early childhood development and associated factors among children under 5 years old in Kolfe Keraniyo Sub City, Addis Ababa, Ethiopia: A cross-sectional study. [PDF]

Medicine (Baltimore)
Dagnaw M, Indracanti M, Rout E, Kedir Z, Arage SM.   +4 more
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Public perceptions of mortality studies in conflict-affected areas of the Eastern Mediterranean Region: an exploratory study. [PDF]

Confl Health
Mahgoub EAA, Alshalah A, El Halabi F, Mamoun M, Fare'a AAM, Elomeiri L, Alazzawi S, Mohamud AK, Awn AMSA, Ahmed MAAS, Zibara Z, Alhamwi F, Abdelmoemen NMA, Houri NJ, Al Merhabi M, Alftaeih OA, Farah MAA, Ali MAA, Ferrario A.   +18 more
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Adding Value to Cassava Genetic Resources Conserved at CIAT-Part I: A Review of Fifty Years of Collection, Conservation, Characterization and Distribution. [PDF]

Plants (Basel)
Hershey CH, Aranzales R E, Jaramillo O G, Manrique-Carpintero NC, Velez-Tobon ML, Wenzl P.   +5 more
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source