Results 121 to 130 of about 6,053,313 (287)

Gut Microbiota‐Isoallolithocholic Acid Crosstalk Promotes Calcium Oxalate Kidney Stone Formation via PARP1‐Mediated Parthanatos

Advanced Science, EarlyView.
ABSTRACT Bile acids have been implicated in calcium oxalate (CaOx) nephrolithiasis. Here, we employ multi‐omics approaches to identify isoallolithocholic acid (isoalloLCA) as the key bile acid elevated in the feces, serum, kidney, and urine of CaOx rats, confirmed by spatial metabolomics.
Zijian Zhou, Ruixi Yu, Xuan Zhou, Feng Shi, Zeyu Lin, Peng Gao, Lujia Wang, Ninghan Feng, Zhong Wu, Dawei Wang   +9 more
wiley   +1 more source

Evaluating acoustic signals to reduce avian collision risk. [PDF]

PeerJ, 2022
Thady RG, Emerson LC, Swaddle JP.
europepmc   +1 more source

Magnetic Water Cleaning of Estrogens via Tight yet Dynamic Binding to Nanoparticles

Advanced Science, EarlyView.
Micropollution is one of the big challenges humanity faces with estrogen hormones being emerging pollutants of concern. Here, a supramolecular design strategy is presented that generates a simple nano‐adsorbent material to magnetically remove low‐concentrated estrogens from water.
Lukas Müller, Philip Maier, Dustin Vivod, Wenke Müller, Nikolaj Lopatik, Theresa Maria Schichtl, Julia Fröhlich, Irene Kraus, Marten Huck, Wieland Corts, Clodomiro Cafolla, Lukas Ruhm, Henrik Gaß, Johannes Voß, Jiwon Byun, Linda Rockmann, Guido Grundmeier, Kislon Voïtchovsky, Hans‐Georg Steinrück, Erdmann Spiecker, Sevim Dalabasmaz, Monika Pischetsrieder, Eike Brunner, Ralf Schweins, Dirk Zahn, Marcus Halik   +25 more
wiley   +1 more source

Study on the Safety Distance of Multi-point Mooring FPSO in Tandem Offloading Operation

Shiyou jixie, 2019
For the multi-point mooring FPSO tandem offloading operation plan in 1500 m water depth, the safety distance of the tandem offloading under the extreme sea conditions of wind and wave in different recurrence interval in the South China Sea is studied ...
Zhao Yu, Wang Yingying, Hu Zhongqian, Wang Honghong, Zheng Wei, Yang Chao   +5 more
doaj  

Providing a detailed estimate of mortality using a simulation-based collision risk model. [PDF]

PLoS One, 2022
Horne N, Culloch RM, Schmitt P, Wilson B, Dale AC, Houghton JDR, Kregting LT.   +6 more
europepmc   +1 more source

A Reconfigurable Memristive Spiking Neuron Enabling Advanced Neuromorphic Computing

Advanced Science, EarlyView.
Pek Jun Tiw and co‐workers develop a reconfigurable memristive neuron that can exhibit four spiking behaviors with freely tunable spike train parameters. The neuron supports multiplexed spike encoding of multiple pieces of information. It also supports advanced neural network strategies, such as neural heterogeneity and dynamic mode switching ...
Pek Jun Tiw, Yuqi Li, Zhongyuan Li, Qihang Ding, Yuzhe Wang, Jiarong Wang, Yuchao Yang   +6 more
wiley   +1 more source

Global collision-risk hotspots of marine traffic and the world's largest fish, the whale shark. [PDF]

Proc Natl Acad Sci U S A, 2022
Womersley FC, Humphries NE, Queiroz N, Vedor M, da Costa I, Furtado M, Tyminski JP, Abrantes K, Araujo G, Bach SS, Barnett A, Berumen ML, Bessudo Lion S, Braun CD, Clingham E, Cochran JEM, de la Parra R, Diamant S, Dove ADM, Dudgeon CL, Erdmann MV, Espinoza E, Fitzpatrick R, Cano JG, Green JR, Guzman HM, Hardenstine R, Hasan A, Hazin FHV, Hearn AR, Hueter RE, Jaidah MY, Labaja J, Ladino F, Macena BCL, Morris JJ, Norman BM, Peñaherrera-Palma C, Pierce SJ, Quintero LM, Ramírez-Macías D, Reynolds SD, Richardson AJ, Robinson DP, Rohner CA, Rowat DRL, Sheaves M, Shivji MS, Sianipar AB, Skomal GB, Soler G, Syakurachman I, Thorrold SR, Webb DH, Wetherbee BM, White TD, Clavelle T, Kroodsma DA, Thums M, Ferreira LC, Meekan MG, Arrowsmith LM, Lester EK, Meyers MM, Peel LR, Sequeira AMM, Eguíluz VM, Duarte CM, Sims DW.   +68 more
europepmc   +1 more source

Natural Product Toosendanin Suppresses the Malignant Development of Skin Melanoma by Targeting BNC2 for Degradation

Advanced Science, EarlyView.
BNC2 exhibits context‐dependent opposing functions across multiple cancer types. This study reveals BNC2 as an oncogenic driver of melanoma proliferation and metastasis through transcriptional activation of PIK3CA. The natural compound TSN simultaneously degrades BNC2 and its oncogenic partner SMAD3 via CRBN‐dependent ubiquitination.
Hui Dai, Xin Mei Zhang, Jing Cheng Zhang, Xu Ting Deng, Qiao Liu, Mustafa Hussein Ali, Fang Zhou Yin, Wu Yin   +7 more
wiley   +1 more source

Quantitative Visualization of Intracellular Nanometabolism Using Peak‐Shifted Dual‐State Emissive FRET Nanoprobes

Advanced Science, EarlyView.
This study reveals the long‐elusive intracellular dissolution mechanism of carrier‐free nanomedicines. By utilizing peak‐shifted dual‐state emissive FRET nanoprobes (PDFNPs) that undergo a distinct ratiometric fluorescence peak shift upon disassembly, we achieve real‐time, quantitative tracking of dissolution kinetics in live cells.
Farsai Taemaitree, Jinwoo Sung, Yutaro Miki, Ryuju Suzuki, Yoshitaka Koseki, Kunikazu Ishii, Minsang Kim, Keita Tanita, Kota Sato, Toru Nakazawa, Satoshi Katsube, Daisuke Unabara, Tasuku Hamaguchi, Keisuke Kawakami, Koji Yonekura, Akihide Hibara, Atsushi Wakamiya, Hiroshi Uji‐I, Hitoshi Kasai   +18 more
wiley   +1 more source

Flight heights obtained from GPS versus altimeters influence estimates of collision risk with offshore wind turbines in Lesser Black-backed Gulls Larus fuscus. [PDF]

Mov Ecol, 2023
Johnston DT, Thaxter CB, Boersch-Supan PH, Davies JG, Clewley GD, Green RMW, Shamoun-Baranes J, Cook ASCP, Burton NHK, Humphreys EM.   +9 more
europepmc   +1 more source