Results 111 to 120 of about 897,221 (299)

Targeting Histone Chaperone FACT Complex Overcomes 5-Fluorouracil Resistance in Colon Cancer [PDF]

, 2019
Heyu Song, Jiping Zeng, Shrabasti Roychoudhury, Pranjal Biswas, Bhopal Mohapatra, Sutapa Ray, Kayvon Dowlatshahi, Jing Wang, Vimla Band, Geoffrey A. Talmon, Kishor K. Bhakat   +10 more
openalex   +1 more source

Silencing Myostatin Using In Vivo Self‐Assembled siRNA Protects Against Cancer‐ and Dexamethasone‐Induced Muscle Atrophy

Advanced Healthcare Materials, EarlyView.
This study reports an in vivo self‐assembled siRNA strategy that enables the liver to generate small extracellular vesicles (sEVs) tagged with a muscle‐targeting peptide (MSP) and naturally loaded with myostatin (MSTN)‐siRNA. These MSP‐tagged sEVs are systemically delivered to skeletal muscle, efficiently silence MSTN, promote muscle hypertrophy, and ...
Xin Yin, Azhar Anwar, Jiehao Chen, Qinghao Sun, Likun Zhou, Jie Tang, Jingwei Guo, Linbo Yan, Yongci Chen, Feng Yin, Chen‐Yu Zhang, Zigang Li, Jizheng Ma, Liyuan Sheng, Xi Chen   +14 more
wiley   +1 more source

Loss of claudin-3 expression induces IL6/gp130/Stat3 signaling to promote colon cancer malignancy by hyperactivating Wnt/β-catenin signaling

, 2017
Rizwan Ahmad, Balawant Kumar, Zhuo Chen, Xu Chen, Dominik Müller, Subodh M. Lele, M. Kay Washington, Surinder K. Batra, Punita Dhawan, Amar B. Singh   +9 more
openalex   +2 more sources

Cyclic Peptide–Polymer Conjugate Nanotubes for Delivery of SN‐38 in Treatment of Colorectal Cancer Model

Advanced Healthcare Materials, EarlyView.
This study develops cyclic peptidepolymer conjugate nanotubes with hydrophobic, drug‐rich cores to enhance drug loading and stability, and demonstrates their responsive disassembly, pharmacokinetics, and anti‐tumour efficacy in colorectal cancer models using the anticancer drug SN‐38.
Sophie K. Hill, Min Zeng, Santhosh Kalash Rajendrakumar, Robert Dallmann, Sébastien Perrier   +4 more
wiley   +1 more source

Metallofullerenol Sc3N@C80(OH)18: A New Generation Radioprotector Protecting Human Erythrocytes Against Multiple Biochemical Damage Modes Upon Gamma Irradiation, Identifying It as a Scavenger of Short‐ and Long‐Lived Radicals

Advanced Healthcare Materials, EarlyView.
Metallofullerenol Sc3N@C80(OH)18 demonstrates strong radioprotective properties as a scavenger of both short‐ and long‐lived radicals. The study reveals protection of human erythrocytes from γ‐radiation–induced biochemical damage via post‐irradiation removal of primary and secondary reactive oxidants, supported by pulse radiolysis kinetics.
Jacek Grebowski, Maciej Studzian, Szymon Lekki‐Porebski, Anna Konarska, Marian Wolszczak, Grzegorz Litwinienko, Lukasz Pulaski   +6 more
wiley   +1 more source

The Impact of Primary Tumor Location on Long-Term Survival in Patients Undergoing Hepatic Resection for Metastatic Colon Cancer

, 2017
John M. Creasy, Eran Sadot, Bas Groot Koerkamp, Joanne F. Chou, Mithat Gönen, Nancy E. Kemeny, Leonard B. Saltz, Vinod P. Balachandran, T. Peter Kingham, Ronald P. DeMatteo, Peter J. Allen, William R. Jarnagin, Michael I. D’Angelica   +12 more
openalex   +2 more sources

MicroRNA-340-5p inhibits colon cancer cell migration via targeting of RhoA [PDF]

, 2020
Anwar Algaber, Amr Al‐Haidari, Raed Madhi, Milladur Rahman, Ingvar Syk, Henrik Thorlacius   +5 more
openalex   +1 more source

Curcumin Loaded Eudragit S100/PLGA Nanoparticles in Treatment of Colon Cancer: Formulation, Optimization, and in-vitro Cytotoxicity Study [PDF]

, 2021
Apeksha Saraf, Nidhi Dubey, Nitin Dubey, Mayank Sharma   +3 more
openalex   +1 more source

Colonic Mucormycosis [PDF]

American Journal of Gastroenterology, 2012
S, Rodrigues, L, Santos, J, Nuak, J, Pardal, J A, Sarmento, G, Macedo   +5 more
openaire   +2 more sources

Harnessing Next‐Generation 3D Cancer Models to Elucidate Tumor‐Microbiome Crosstalk

Advanced Healthcare Materials, EarlyView.
Centralizes the microbiome within 3D tumor‐microbiome model platforms, including spheroids, organoids, 3D‐bioprinted constructs, and microfluidic chips, each enabling structured host‐tumor‐microbe studies. These systems support bacterial colonization, facilitating investigation of microbial impacts on tumor growth, immunity, and therapy. The microbiome
Marina Green Buzhor, Giuseppe Longobardi, Or Kandli, Anne Krinsky, Opal Avramoff, Anshika Katyal, Koren Salomon, Adan Miari, Dana Venkert, Tania T. Barnatan, América García Alvarado, Shahar Greenberg, Ronit Satchi‐Fainaro   +12 more
wiley   +1 more source