Results 81 to 90 of about 1,279,401 (299)

Genome-wide methylation analysis of human colon cancer reveals similar hypo- and hypermethylation at conserved tissue-specific CpG island shores

Nature Genetics, 2008
For the past 25 years, it has been known that alterations in DNA methylation (DNAm) occur in cancer, including hypomethylation of oncogenes and hypermethylation of tumor suppressor genes.
R. Irizarry, C. Ladd-Acosta, Bo Wen, Zhijin Wu, C. Montano, P. Onyango, H. Cui, Kevin Gabo, Michael A Rongione, M. Webster, Hong Ji, J. Potash, S. Sabunciyan, A. Feinberg   +13 more
semanticscholar   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

Predictors for temporary stomas non-closure among non-metastatic rectal cancer patients undergoing curative resection: a retrospective analysis

World Journal of Surgical Oncology
Background The primary treatment for non-metastatic rectal cancer is curative resection. However, sphincter-preserving surgery may lead to complications.
Chia-Chien Hsu, Wen-Sy Tsai, Tzong-yun Tsai, Jeng-Fu You, Chien-Yuh Yeh, Pao-Shiu Hsieh, Reiping Tang, Shu-Huan Huang   +7 more
doaj   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

The Intestinal Transport of Bovine Milk Exosomes Is Mediated by Endocytosis in Human Colon Carcinoma Caco-2 Cells and Rat Small Intestinal IEC-6 Cells [PDF]

, 2015
Tovah Wolf, Scott Baier, Janos Zempleni
openalex   +1 more source

ACLY facilitates colon cancer cell metastasis by CTNNB1

Journal of experimental & clinical cancer research : CR, 2019
Colon cancer is the second leading cancer worldwide. Recurrent disease and chemotherapeutic drug resistance are very common in the advanced stage of colon cancer.
Jun Wen, Xuejie Min, Mengqin Shen, Qian Hua, Yuan Han, Li Zhao, Liu Liu, Gang Huang, Jianju Liu, Xiaoping Zhao   +9 more
semanticscholar   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Native Cyclodextrin-Based Metal–Organic Frameworks (MOFs): Synthesis, Characterization, and Potential Applications in Food Industry

Molecules
Metal–organic frameworks (MOFs) have become a highly usable system in various sectors because of their highly ordered structure and high porosity providing them with high storage capacity.
Siddanth Saxena, Manuel J. Lis
doaj   +1 more source

Identification, isolation and characterization of human LGR5-positive colon adenoma cells [PDF]

, 2018
Michael K. Dame, Durga Attili, Shannon D. McClintock, Priya H. Dedhia, Peter Ouillette, Olaf Hardt, Alana M. Chin, Xiang Xue, Julie Laliberté, Erica L. Katz, Gina M. Newsome, David R. Hill, Alyssa J. Miller, Yu-Hwai Tsai, David Agorku, Christopher Altheim, Andreas Bosio, B Simon, Linda C. Samuelson, Jay Stoerker, Henry D. Appelman, James Varani, Max S. Wicha, Dean E. Brenner, Yatrik M. Shah, Jason R. Spence, Justin A. Colacino   +26 more
openalex   +1 more source

Anticancer effects of Bifidobacteria on colon cancer cell lines [PDF]

, 2021
Zeinab Faghfoori, Mohammad Hasan Faghfoori, Amir Saber, Azimeh Izadi, Ahmad Yari Khosroushahi   +4 more
openalex   +1 more source