Results 11 to 20 of about 1,115,426 (335)

The non-oral infection of larval Echinococcus granulosus induces immune and metabolic reprogramming in the colon of mice

open access: yesFrontiers in Immunology, 2023
BackgroundThe intestinal tract serves as a critical regulator for nutrient absorption and overall health. However, its involvement in anti-parasitic infection and immunity has been largely neglected, especially when a parasite is not transmitted orally ...
Yuying Zhou   +14 more
doaj   +1 more source

Antepartum Antibiotic Treatment Increases Offspring Susceptibility to Experimental Colitis: A Role of the Gut Microbiota. [PDF]

open access: yesPLoS ONE, 2015
Postnatal maturation of the immune system is largely driven by exposure to microbes, and thus the nature of intestinal colonization may be associated with development of childhood diseases that may persist into adulthood.
Peris Mumbi Munyaka   +4 more
doaj   +1 more source

Muc5ac Expression Protects the Colonic Barrier in Experimental Colitis

open access: yesInflammatory Bowel Diseases, 2020
Recent studies highlight the importance of mucins, in particular Muc2, in intestinal homeostasis. Our functional study demonstrates that an alternative secreted mucin, MUC5AC/Muc5ac, is induced in colitis to protect the colonic barrier by limiting host ...
K. Olli   +14 more
semanticscholar   +1 more source

A Review of Colonoscopy in Intestinal Diseases

open access: yesDiagnostics, 2023
Since the development of the fiberoptic colonoscope in the late 1960s, colonoscopy has been a useful tool to diagnose and treat various intestinal diseases.
Seung Min Hong, Dong Hoon Baek
doaj   +1 more source

Application of a new protocol for a study of colonic transit using radiopaque markers in functional constipation for a population with rapid gut transit

open access: yesDentistry and Medical Research, 2023
Background: Indians do not fit the definition of slow transit constipation (STC) according to Western standards because of their quick gut transit. The colonic transit study (CTS) can discriminate between patients with severe specific motility problems ...
Bhavith Remalayam, Varghese Thomas
doaj   +1 more source

Human gut microbiota-reactive DP8α regulatory T cells, signature and related emerging functions

open access: yesFrontiers in Immunology, 2022
In mice, microbiota-induced Tregs both maintain intestinal homeostasis and provide resistance to immuno-pathologies in the adult. Identifying their human functional counterpart therefore represents an important goal.
Francine Jotereau   +6 more
doaj   +1 more source

Comparison of bran, ispaghula, and lactulose on colon function in diverticular disease. [PDF]

open access: yesGut, 1978
Bran, ispaghula (Fybogel), and lactulose were given to three groups of patients with diverticular disease for four weeks. Faecal weights, bile acids, fat and electrolytes, transit time, and colonic motility were estimated before and after treatment. Stool weight increased, notably with Fybogel.
J Pritchard   +3 more
openaire   +3 more sources

Short-term mucosal disruption enables colibactin-producing E. coli to cause long-term perturbation of colonic homeostasis

open access: yesGut Microbes, 2023
Colibactin, a bacterial genotoxin produced by E. coli strains harboring the pks genomic island, induces cytopathic effects, such as DNA breaks, cell cycle arrest, and apoptosis.
Christine Harnack   +5 more
doaj   +1 more source

Colonic Butyrate-Producing Communities in Humans: an Overview Using Omics Data

open access: yesmSystems, 2017
Studies focusing on taxonomic compositions of the gut microbiota are plentiful, whereas its functional capabilities are still poorly understood. Specific key functions deserve detailed investigations, as they regulate microbiota-host interactions and ...
M. Vital, A. Karch, D. Pieper
semanticscholar   +1 more source

Clinical Parasitology and Parasitome Maps as Old and New Tools to Improve Clinical Microbiomics

open access: yesPathogens, 2021
A growing body of evidence shows that dysbiotic gut microbiota may correlate with a wide range of disorders; hence, the clinical use of microbiota maps and fecal microbiota transplantation (FMT) can be exploited in the clinic of some infectious diseases.
Stefania Pane   +5 more
doaj   +1 more source

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