The Brain-Gut-Microbiome Axis. [PDF]
, 2018 Preclinical and clinical studies have shown bidirectional interactions within the brain-gut-microbiome axis. Gut microbes communicate to the central nervous system through at least 3 parallel and interacting channels involving nervous, endocrine, and ...
Kalani, Amir +3 more
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Cells, 2022 Thanks to the latest developments in mass spectrometry, software and standards, metaproteomics is emerging as the vital complement of metagenomics, to make headway in understanding the actual functioning of living and active microbial communities. Modern
Céline Henry +5 more
doaj +1 more source
Nod2 Deficiency in mice is Associated with Microbiota Variation Favouring the Expansion of mucosal CD4+ LAP+ Regulatory Cells [PDF]
, 2018 Nucleotide-binding Oligomerization Domain-2 (NOD2) mutations are associated with an increased risk to develop Crohn's Disease. In previous studies, we have shown that Nod2-/- mice manifest increased proportion of Lamina Propria (LP) CD4+ LAP+ Foxp3 ...
Boirivant, M. +9 more
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The Interaction of Large Bowel Microflora with the Colonic Mucus Barrier
International Journal of Inflammation, 2010 The colonic mucus barrier is the first line of defence that the underlying mucosa has against the wide range of potentially damaging agents of microbial, endogenous, and dietary origin that occur within the colonic lumen.
Jeffrey P. Pearson, Iain A. Brownlee
doaj +1 more source
مجله دانشکده پزشکی اصفهان, 2018 Background: Chronic functional constipation is one of functional gastrointestinal disorders. Constipation has negative impact on quality of life (QOL). Pharmacological and non-pharmacological treatments are considered for constipation.
Mansour Bahardoost +6 more
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Interleukin 31 mediates MAP kinase and STAT1/3 activation in intestinal epithelial cells and its expression is upregulated in inflammatory bowel disease [PDF]
, 2007 Background/aim: Interleukin 31 (IL31), primarily expressed in activated lymphocytes, signals through a heterodimeric receptor complex consisting of the IL31 receptor alpha (IL31R\textgreeka) and the oncostatin M receptor (OSMR). The aim of this study was
Auernhammer, Christoph J. +6 more
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The Proinflammatory Role of Guanylate-Binding Protein 5 in Inflammatory Bowel Diseases
Frontiers in Microbiology, 2022 NLRP3 inflammasome is implicated in the pathogenesis of inflammatory bowel diseases (IBD). Since guanylate-binding protein 5 (GBP5) induces the NLRP3 inflammasome activity, we aim to investigate the potential role of GBP5 in IBD pathogenesis.
Yichen Li +9 more
doaj +1 more source
EFSUMB Recommendations and Guidelines for Gastrointestinal Ultrasound - Part 1: Examination Techniques and Normal Findings (Long version). [PDF]
, 2016 ▼ In October 2014 the European Federation of Societies for Ultrasound in Medicine and Biology formed a Gastrointestinal Ultrasound (GIUS) task force group to promote the use of GIUS in a clinical setting.
Calabrese, E. +16 more
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Dietary-based gut flora modulation against Clostridium difficile onset [PDF]
, 2007 Clostridium difficile infection is a frequent complication of antibiotic therapy in hospitalised patients, which today is attracting more attention than ever and has led to its classification as a 'superbug'.
Gibson, G.R. +2 more
core +1 more source
To respond or not to respond - a personal perspective of intestinal tolerance [PDF]
, 2018 For many years, the intestine was one of the poor relations of the immunology world, being a realm inhabited mostly by specialists and those interested in unusual phenomena.
A Besredka +142 more
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