Results 121 to 130 of about 177,298 (308)

Oxidized Low-Density Lipoprotein Induces Reactive Oxygen Species-Dependent Proliferation of Intestinal Epithelial Cells

Pharmaceuticals
Background/Objectives: Oxidized low-density lipoprotein (ox-LDL) is a proinflammatory particle associated with various diseases and affects cell proliferation and viability in multiple cell types.
Eddy E. Gonzalez-Horta, Juan F. Burgueno, María J. Leiva, Carla Villavicencio, Fernando I. Kawaguchi, Hajar Hazime, Fátima Reyes, Viana Manrique-Suárez, Natalie C. Parra, Maria T. Abreu, Jorge R. Toledo   +10 more
doaj   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Pathological changes in seals in Swedish waters: the relation to environmental pollution [PDF]

, 2007
This thesis concerns the disease situation for the three seal species that inhabit the Swedish coastal waters; the grey seal (Halichoerus grypus), the ringed seal (Phoca hispida botnica) and the harbour seal (Phoca vitulina).
Bergman, Anders
core  

Possible role of human ribonuclease dicer in the regulation of R loops

FEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik, Paulina Krzeminska, Anna Kurzynska‐Kokorniak   +2 more
wiley   +1 more source

Colonic dysmotility and morphological abnormality frequently detected in Japanese patients with irritable bowel syndrome

Intestinal Research, 2017
Background/Aims: Colonoscopy and computed tomography (CT) are used primarily to exclude organic diseases in patients with irritable bowel syndrome (IBS), rather than to assess the pathophysiology of IBS.
Takeshi Mizukami, Shinya Sugimoto, Tatsuhiro Masaoka, Hidekazu Suzuki, Takanori Kanai   +4 more
doaj   +1 more source

Effect of Methylcellulose on Rectal and Colonic Pressures in Treatment of Diverticular Disease [PDF]

, 1972
John Hodgson
openalex   +1 more source

Protein O‐glycosylation in the Bacteroidota phylum

FEBS Open Bio, EarlyView.
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns, Dennis Svedberg, André Mateus   +2 more
wiley   +1 more source

Colonic Spirochetosis in a 60-Year-Old Immunocompetent Patient

Journal of Investigative Medicine High Impact Case Reports, 2016
Spirochetes, a genetically and morphologically distinct group of bacteria, are thin, spiral-shaped, and highly motile. They are known causes of several human diseases such as syphilis, Lyme disease, relapsing fever, and leptospirosis. We report a case of
Taiwo Ngwa MD, Jennifer L. Peng MD, Euna Choi MD, Sucharat Tayarachakul BS, MPH, Suthat Liangpunsakul MD, MPH   +4 more
doaj   +1 more source

Post-Translational Modifications of Transcription Factors Harnessing the Etiology and Pathophysiology in Colonic Diseases. [PDF]

Int J Mol Sci, 2020
Hsu CY, Fu SH, Chien MW, Liu YW, Chen SJ, Sytwu HK.   +5 more
europepmc   +1 more source

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran, Ruchi A. Patel, Amogh Chariyamane, Ratna B. Ray   +3 more
wiley   +1 more source