Results 71 to 80 of about 1,118,799 (244)

Colony

open access: yes
Silent. Footage for the Colony Motor Inn. Includes hotel room service delivering a complimentary continental breakfast and turning on television set, and woman in bathing suit sitting on the deck of a swimming ...
Spreitz, Karl, 1927-2016
core   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Economic Growth in the Cape Colony

open access: yes, 2018
The dataset 'Economic Growth in the Cape Colony' was downloaded from the Centre for Global Economic History website, of Utrecht University (http://cgeh.nl/economic-growth-cape-colony).
Jan Luiten van Zanden (Utrecht University, International Institute of Social History)   +1 more
core   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

open access: yesMolecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh   +11 more
wiley   +1 more source

Near-Optimum Soft-Output Ant-Colony-Optimization Based Multiuser Detection for the DS-CDMA uplink

open access: yes, 2008
In this contribution, a novel soft-output Ant Colony Optimization (ACO) based Multi-User Detector (MUD) is proposed for the synchronous Direct-Sequence Code-Division- Multiple-Access (DS-CDMA) uplink.
Yang, L.-L.   +11 more
core   +1 more source

Untitled [Colony Motor Inn]

open access: yes
Silent. Footage for the Colony Motor Inn.
Spreitz, Karl, 1927-2016
core   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Comparison of Multiple Carbapenemase Tests Based on an Unbiased Colony-Selection Method

open access: yesBiomedicines
Carbapenemase-producing organisms (CPOs) present a major threat to public health, demanding precise diagnostic techniques for their detection. Discrepancies among the CPO tests have raised concerns, partly due to limitations in detecting bacterial ...
Hsin-Yao Wang   +9 more
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Enhancing DoS Detection in WSNs Using Enhanced Ant Colony Optimization Algorithm

open access: yesIEEE Access
The increasing use of Wireless Sensor Networks (WSNs) is leading to network traffic growth as data exchange among WSN nodes increases. Protecting WSNs from Denial of Service (DoS) attacks is essential for enhancing data security and avoiding ...
Rana Al-Rawashdeh   +4 more
doaj   +1 more source

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