Results 71 to 80 of about 466,071 (297)
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Identifikasi Motif Jepara pada Ukiran dengan Memanfaatkan Convolutional Neural Network
Jurnal Nasional Teknik Elektro dan Teknologi Informasi, 2020 Semakin berkembang motif ukiran, semakin beragam bentuk dan variasinya. Hal ini menyulitkan dalam menentukan suatu ukiran bermotif Jepara. Pada makalah ini, metode transfer learning dengan FC yang dikembangkan dimanfaatkan untuk mengidentifikasi motif ...
Sandhopi +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Journal of Agricultural Sciences, 2019 Segmentation is an important part of each machine vision system that has a direct relationship with the final system accuracy and performance. Outdoors segmentation is often complex and difficult due to both changes in sunlight intensity and the ...
Yousef Abbaspour-gilandeh +2 more
doaj +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
A Coloring Problem in Hamming Spaces
European Journal of Combinatorics, 1997 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +1 more source
Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
Exploring Image Decolorization: Methods, Implementations, and Performance Assessment
Applied SciencesDecolorization is an image processing technique that converts a color input image into a grayscale image. This paper discusses the decolorization process and provides an overview of the methods based on the different principles used: basic conversion ...
Ivana Žeger +3 more
doaj +1 more source