Results 101 to 110 of about 1,203,673 (294)
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Cumhuriyet Dental Journal, 2018 Amaç: Bu çalışmanın amacı farklı içeceklere, ağız çalkalama solüsyonlarına ve diş macunlarına maruz bırakılan kompomer rezinlerin renk stabilitesini değerlendirmektir.Gereç ve yöntemler: İçecek, ağız çalkalama solüsyonu ve diş macunu grupları için 5’er ...
Bilal Özmen, Yasemin Nayir
doaj +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Electroweak Vacuum Stability and Diphoton Excess at 750 GeV
, 2016 Recently, both ATLAS and CMS collaborations at the CERN Large Hadron Collider (LHC) have announced their observations of an excess of diphoton events around the invariant mass of $750~{\rm GeV}$ with a local significance of $3.6\sigma$ and $2.6\sigma ...
Zhang, Jue, Zhou, Shun
core +2 more sources
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Applied SciencesNewly developed 3D-printed polymer materials are used for denture base fabrication. The aim of the present study was to evaluate the color stability of two new 3D-printed resins, a hard PPMA-based and a soft Urethane-based resin, in relation to a ...
Vasileios Vergos +4 more
doaj +1 more source
Nanophotonics, 2018 By incorporating ultrathin (80, low correlated color temperature of
Miao Yanqin +9 more
doaj +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source