Results 121 to 130 of about 5,332,530 (372)

Menopause and colorectal cancer [PDF]

British Journal of Cancer, 2000
Post-menopausal women who have never used hormone replacement therapy have a higher risk of colon, but not rectal, cancer than do premenopausal women of the same age, socio-cultural class and dietary habits. Such risk increase seems to last about 10 years and to be restricted to lean women, a group who have lower levels of oestradiol after ovarian ...
Alessandra Tavani, C. La Vecchia, C. La Vecchia, R. Talamini, Silvano Gallus, Silvia Franceschi, Eva Negri   +6 more
openaire   +4 more sources

Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer

Molecular Oncology, EarlyView.
This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu, Fenglin Shen, Yang Liu, Ziqing Zhong, Yongling Chen, Zhiyuan Xia, Cuiju Mo, Hongxiu Yu   +7 more
wiley   +1 more source

A hybrid of multiple linear regression clustering model with support vector machine for colorectal cancer tumor size prediction [PDF]

, 2019
This study proposed the new hybrid model of Multiple Linear Regression Clustering (MLRC) combined with Support Vector Machine (SVM) to predict tumor size of colorectal cancer (CRC).
Ismail, Shuhaida, Kamardan, Muhamad Ghazali, Rusiman, Mohd Saifullah, Shafi, Muhammad Ammar   +3 more
core   +1 more source

Polyfunctional CD8+CD226+RUNX2hi effector T cells are diminished in advanced stages of chronic lymphocytic leukemia

Molecular Oncology, EarlyView.
CD226+CD8+ T cells express elevated levels of RUNX2, exhibit higher proliferation capacity, cytokines and cytolytic molecules expression, and migratory capacity. In contrast, CD226−CD8+ T cells display an exhausted phenotype associated with the increased expression of co‐inhibitory receptors and impaired effector functions.
Maryam Rezaeifar, Shima Shahbaz, Anthea C. Peters, Spencer B. Gibson, Shokrollah Elahi   +4 more
wiley   +1 more source

Screening and Surveillance for the Early Detection of Colorectal Cancer and Adenomatous Polyps, 2008: A Joint Guideline from the American Cancer Society, the US Multi‐Society Task Force on Colorectal Cancer, and the American College of Radiology * †

Ca, 2008
In the United States, colorectal cancer (CRC) is the third most common cancer diagnosed among men and women and the second leading cause of death from cancer.
B. Levin, D. Lieberman, B. McFarland, Robert A Smith, D. Brooks, Kimberly S. Andrews, C. Dash, F. Giardiello, S. Glick, T. Levin, Perry Pickhardt, D. Rex, A. Thorson, S. Winawer   +13 more
semanticscholar   +1 more source

Multiplicity of fibronectin-binding alpha V integrin receptors in colorectal cancer. [PDF]

, 1996
Current data from in vitro and in vivo animal models indicate that fibronectin-binding integrin receptors expressed by colon cancer cells may regulate tumour growth.
Agrez, MV, Anseline, P, Bates, RC, Ferguson, N, Mitchell, D, Sheppard, D, Wilson, N   +6 more
core   +2 more sources

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

Molecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy, Heather Fairfield, Victoria E. DeMambro, Samaa Fadel, Carlos A. Gartner, Michelle Karam, Christian Potts, Princess Rodriguez, Ya‐Wei Qiang, Habib Hamidi, Xiangnan Guan, Calvin P. H. Vary, Michaela R. Reagan   +12 more
wiley   +1 more source

Clinical score for predicting recurrence after hepatic resection for metastatic colorectal cancer: analysis of 1001 consecutive cases.

Annals of Surgery, 1999
OBJECTIVE There is a need for clearly defined and widely applicable clinical criteria for the selection of patients who may benefit from hepatic resection for metastatic colorectal cancer. Such criteria would also be useful for stratification of patients
Y. Fong, J. Fortner, Ruth L. Sun, M. Brennan, L. Blumgart   +4 more
semanticscholar   +1 more source

Pulmonary Metastasectomy in Colorectal Cancer: updated analysis of 93 randomized patients – control survival is much better than previously assumed

Colorectal Disease, 2020
Lung metastases from colorectal cancer are resected in selected patients in the belief that this confers a significant survival advantage. It is generally assumed that the 5‐year survival of these patients would be near zero without metastasectomy.
M. Milošević, J. Edwards, David Tsang, J. Dunning, M. Shackcloth, T. Batchelor, A. Coonar, J. Hasan, Brian Davidson, A. Marchbank, S. Grumett, N. Williams, F. Macbeth, V. Farewell, T. Treasure   +14 more
semanticscholar   +1 more source

The role of perineural invasion in predicting survival in patients with primary operable colorectal cancer: a systematic review [PDF]

, 2017
Perineural invasion is a clear route for cancer cell spread however, the role of nerves in cancer progression is relatively unknown. Recent work would suggest that nerves can actively infiltrate the tumour microenvironment and stimulate cancer cell ...
Going, James, Horgan, Paul, McMillan, Donald C., Van Wyk, Hester   +3 more
core   +1 more source