Results 61 to 70 of about 4,157,974 (295)

Nanoknife and hepatic embolization for colorectal cancer liver metastases

, 2020
Effective techniques for local management of unresectable colorectal liver metastases are important tools for a substantial number of patients. Novel approaches and technical improvement of older techniques have been developed to target liver lesions ...
Santos, Lucas Vieira dos, Lopes, Gilberto de Lima, Cruz, Marcelo R. S.   +2 more
core   +2 more sources

Comparison of gene mutations of liver metastases to the primary tumor in colorectal cancer: lessons from a small cohort

Frontiers in Oncology
IntroductionUpfront molecular diagnostics are used to characterize genetic features of colorectal cancer, guiding therapy. Since colorectal cancer is usually surgically resected, these samples are used for such characterizations.
Erzsebet Rásó, Tamas Barbai, Laura Vizkeleti, Andrea Uhlyarik, József Tímár   +4 more
doaj   +1 more source

Surgical treatment of colorectal cancer liver metastases

Acta Medica Lituanica, 2011
Background. Colorectal cancer is a major health problem. Approximately 25% of the patients present with liver metastases at initial diagnosis and more than 50% develop metastases in the course of illness.
Dainius ŠIMČIKAS, Marius PAŠKONIS, Vitalijus SOKOLOVAS, Eligijus POŠKUS, Kęstutis STRUPAS   +4 more
doaj   +1 more source

Role of surgery in colorectal cancer liver metastases

World Journal of Gastroenterology, 2014
Colorectal carcinoma (CRC) is the third most common cancer, and approximately 35%-55% of patients with CRC will develop hepatic metastases during the course of their disease. Surgical resection represents the only chance of long-term survival. The goal of surgery should be to resect all metastases with negative histological margins while preserving ...
Özgür, Akgül, Erdinç, Çetinkaya, Şiyar, Ersöz, Mesut, Tez   +3 more
openaire   +2 more sources

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

The multifaceted roles of lysosomes in cancer

Molecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source

Comparison of the Response Evaluation Criteria in Solid Tumors with Volumetric Measurement for Evaluation of Response and Overall Survival with Liver Metastases from Colorectal Cancer

대한영상의학회지, 2019
Purpose The aim of this study was to compare the measurements of diameter and volume of hepatic metastases from CT images with the overall survival and tumor response, in patients with unresectable liver metastases of colorectal cancer treated with a ...
In Seon Lee, Seung Joon Choi, Cho Rong Seo, Jun Seong Kim   +3 more
doaj   +1 more source

Management of Colorectal Cancer Liver Metastases

Cancers
Ivey et al [...]
Jakob A. Durden, Ioannis A. Ziogas, Dimitrios P. Moris, Ana L. Gleisner   +3 more
openaire   +2 more sources

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

Molecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi, Sang‐Hyeon Yoo, Ki‐Jong Rhee   +2 more
wiley   +1 more source

Metastasectomy of Combined Liver and Lung Colorectal Cancer Metastases

, 2015
The liver is the exclusive site of metastasis in approximately 30% to 50% of patients with stage IV colorectal cancer, whereas lung metastasis occurs in 10% to 20% of patients.
Abdalla, Eddie, Contreras, Carlo
core   +1 more source