Results 31 to 40 of about 9,868 (158)

Clinicopathologic and Molecular Profiles of Microsatellite Unstable Barrett Esophagus-associated Adenocarcinoma [PDF]

, 2014
Microsatellite instability (MSI) has been reported in various tumors, with colon cancer as the prototype. However, little is known about MSI in Barrett esophagus (BE)-associated adenocarcinoma.
Cohen, Cynthia, Demicco, Elizabeth G., Farris, Alton B., Finberg, Karin E., Fukuoka, Junya, Gaissert, Henning Arthur, Iafrate, Anthony John, Lauwers, Gregory Y., Le, Long Phi, Mandal, Rajni, Miller, Julie, Mino-Kenudson, Mari, Zukerberg, Lawrence R.   +12 more
core   +1 more source

Postradiation Histiocytic Sarcoma in the Setting of Muir-Torre Syndrome

Case Reports in Pathology, 2018
Hereditary nonpolyposis colorectal carcinoma (HNPCC) is an autosomal dominant genetic disorder characterized by a predisposition towards colorectal carcinoma and other extracolonic neoplasms.
Erin Baumgartner, David Ullman, Jeffrey Adam Jones, Danielle Fasciano, Daniel S. Atherton, Peter Pavlidakey, Deniz Peker   +6 more
doaj   +1 more source

Characterization of sebaceous and non-sebaceous cutaneous manifestations in patients with lynch syndrome: a systematic review. [PDF]

, 2022
A subset of patients with Lynch Syndrome demonstrates cutaneous manifestations of the disorder. Characterization of these Lynch-related skin lesions could help in early recognition of patients with Lynch Syndrome. A broad search of the literature on OVID
Alam, A, Aziz, S, Heelan, K, McVeigh, TP, O'Sullivan, H   +4 more
core   +1 more source

Frequency of hematologic and solid malignancies in the family history of 50 patients with acute myeloid leukemia - a single center analysis.

PLoS ONE, 2019
Background and objectiveThe revised World Health Organization classification of 2016 for myeloid neoplasms and acute leukemia added a section of myeloid neoplasms with germline predisposition. The main objective of our study was to evaluate the frequency
Anne-Sophie Sandner, Ramona Weggel, Yasmin Mehraein, Stephanie Schneider, Wolfgang Hiddemann, Karsten Spiekermann   +5 more
doaj   +1 more source

Incidence and epidemiological features of synchronous and metachronous colorectal cancer

Journal of Coloproctology, 2013
Introduction: patients with sporadic colorectal cancer or cases associated with syndromes are at risk of having synchronous or metachronous cancer. Although it is an important subject, Brazilian data on the subject are scarce.
Eduardo Brambilla, Augusto Cardoso Sgarioni, Guilherme Finger, Guilherme Sartori, Maicon Joel Cimarosti   +4 more
doaj   +1 more source

Molecular pathology of colorectal cancer. [PDF]

, 2014
Colorectal cancer (CRC) is one of the most intensively studied cancer types, partly because of its high prevalence but also because of the existence of its precursor lesions, tubular or villous adenomas, and more recently (sessile) serrated adenomas ...
Bosman, F., Yan, P.
core   +2 more sources

Detección de mutaciones de los genes hMLH1 y hMSH2 del sistema de reparación de malos apareamientos del ADN en familias colombianas sospechosas de cancer colorrectal no polipósico hereditario (síndrome de Lynch).

Biomédica: revista del Instituto Nacional de Salud, 2005
Introducción. El cáncer colorrectal es la segunda causa de morbilidad y mortalidad por cáncer en los países desarrollados. En Colombia es la quinta causa de muerte entre los diferentes cánceres.
Andrea Gómez, Gustavo Salguero, Herbert García, Fabio Aristizábal, Oscar Gutiérrez, Luis Alberto Angel, Jorge Padrón, Carlos Martínez, Humberto Martínez, Omar Malaver, Rosa Barvo, Alejandro Giraldo   +11 more
doaj   +1 more source

Genetic pathways, prevention, and treatment of sporadic colorectal cancer [PDF]

, 2014
Epithelial cancer of the colon and rectum, also known as colorectal cancer (CRC), results from a progressive accumulation of genetic and epigenetic alterations that lead to uncontrolled growth of colonocytes, the cells lining the colon and rectum. CRC is
Imperiale, Thomas F., Loehrer, Patrick J., Lu, Tao, Mundade, Rasika, Prabhu, Lakshmi   +4 more
core   +2 more sources

Duodenal carcinoma at the ligament of Treitz. A molecular and clinical perspective [PDF]

, 2010
Background There is very small occurrence of adenocarcinoma in the small bowel. We present a case of primary duodenal adenocarcinoma and discuss the findings of the case diagnostic modalities, current knowledge on the molecular biology behind small ...
A Berger, A May, A Moglia, A Postgate, A Ross, A Tocchi, AI Neugut, AI Neugut, AK Chong, Alexandros G Georgakilas, Andrew Morfesis, Anthony Daniels, B Lashner, BS Dabaja, BS Lewis, C Beard, C Crawley, C Ell, D Arakawa, D Jigyasu, DL Ciresi, DM Scott-Coombes, E Negri, F Pilleul, G Zuckerman, GM Cobrin, H Markogiannakis, H Yamagami, HH Yen, I Hatzaras, IG Kaklamanos, J Bos, J Cunningham, JA DiSario, JC Saurin, JHPM North, JJ Napierkowski, JM Wheeler, JM Wilson, John E Poulos, JS Berner, K Bilimoria, K Honda, L Gorunova, M Appleyard, M Arai, M Boudiaf, M Efthymiou, M Overman, MA Murray, MJ Horner, N Thompson, P Katsinelos, PDJP Howdle, Peter T Kalogerinis, R Burt, R Kariv, S Bar-Meir, S Gill, S Mehdizadeh, S Roy, SA Gross, SK Lo, SL Han, Stavroula Georgakila, T Haselkorn, T Intner, Thomas Daignualt, V Raptopoulos, W Ross, W Rubinstein, WA Voderholzer, WH Chow, X Chen, Y Katakura, ZZ Ge   +75 more
core   +3 more sources

Phenotypic Heterogeneity by Germline Mismatch Repair Gene Defect in Lynch Syndrome Patients

Acta Médica Portuguesa, 2016
Introduction: Lynch syndrome is the most common form of hereditary colorectal cancer, being also responsible for endometrial and other types of cancers. It is associated with germline mutations in DNA mismatch repair genes and microsatellite instability.
Jorge Hernâni-Eusébio, Elisabete Barbosa   +1 more
doaj   +1 more source