Results 91 to 100 of about 1,819,070 (307)

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Fathers' eye colour sways daughters' choice of both long- and short-term partners [PDF]

open access: yes, 2018
In several species, mate choice is influenced by parental features through sexual imprinting, but in humans evidence is scarce and open to alternative explanations.
Bressan, Paola, Damian, Valeria
core   +2 more sources

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

A Colour Selection System to Better Inform the Colour Forecasting Process [PDF]

open access: yes, 2010
Colour forecasting is a process where attempts are made to accurately forecast colour for fashion-related products that consumers will purchase in the near future.
Cassidy, Tracy Diane   +2 more
core  

Colour Text Segmentation in Web Images Based on Human Perception [PDF]

open access: yes, 2007
There is a significant need to extract and analyse the text in images on Web documents, for effective indexing, semantic analysis and even presentation by non-visual means (e.g., audio).
A. Antonacopoulos   +12 more
core   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Colour Confinement and Deformed Baryons in Quantum Chromodynamics

open access: yes, 2012
The confinement of coloured entities in Quantum Chromodynamics (QCD) is traced to colour singletness of the observed entities. This is believed to arise from colour singlet state of quark-antiquark for mesons and a fully colour antisymmetric state for ...
Abbas A   +9 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Image processing for smart browsing of ocean colour data products and subsequent incorporation into a multi-modal sensing framework [PDF]

open access: yes, 2010
Ocean colour is defined as the water hue due to the presence of tiny plants containing the pigment chlorophyll, sediments and coloured dissolved organic material and so water colour can provide valuable information on coastal ecosystems.
Diamond, Dermot   +5 more
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

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