Results 81 to 90 of about 1,819,070 (307)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

An optical/NIR survey of globular clusters in early-type galaxies III. On the colour bimodality of GC systems

, 2012
The interpretation that bimodal colour distributions of globular clusters (GCs) reflect bimodal metallicity distributions has been challenged. Non-linearities in the colour to metallicity conversions caused by the horizontal branch (HB) stars may be ...
A. L. Chies-Santos, Alves-Brito, Ashman, Ashman, Ashman, Beasley, Beasley, Bica, Bird, Biscardi, Blakeslee, Blakeslee, Brocato, Brodie, Caldwell, Cantiello, Chies-Santos, Chies-Santos, Cohen, Cohen, Côté, Dirsch, E. M. Wehner, Elson, Forbes, Foster, Foster, H. Kuntschner, Harris, J. P. Brodie, J. Strader, Kundu, Larsen, Lee, Liu, M. Cantiello, Maraston, Marigo, Mieske, Muratov, Peng, Peng, Raimondo, Rhode, Richtler, S. S. Larsen, Sohn, Spitler, Stetson, Strader, Strader, Strader, Woodley, Yoon, Yoon, Yoon, Zinn   +56 more
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

“We Can’t Let Go”: Navigating Dance in a (Post-)Conflict Society

Conversations Across the Field of Dance Studies
Violence and precarity in Manipur is its past and current. What becomes of dance when violence spills over to various parts of society? What does it mean to be haunted by unspeakable memories of violence and yet dance for self and community, region and ...
Babina Devi, Debanjali Biswas
doaj   +2 more sources

Enlightened Romanticism: Mary Gartside’s colour theory in the age of Moses Harris, Goethe and George Field [PDF]

, 2012
The aim of this paper is to evaluate the work of Mary Gartside, a British female colour theorist, active in London between 1781 and 1808. She published three books between 1805 and 1808.
Loske, Alexandra
core   +1 more source

X-ray colour-colour selection for heavily absorbed AGN

, 2012
We present a method for the identification of heavily absorbed AGN (NH>10^23 cm^-2) from X-ray photometric data. We do this using a set of XMM-Newton reference spectra of local galaxies for which we have accurate NH information, as described in Brightman
Alexander, Antonucci, Bassani, Brightman, Brightman, Daddi, Della Ceca, Diamond-Stanic, Fiore, Gilli, Guainazzi, Hasinger, Hopkins, Kirpal Nandra, LaMassa, Matt, Murray Brightman, Noguchi, Rush, Spinoglio, Trouille, Turner, Ueda, Ueda   +23 more
core   +1 more source

Study of Rapidity Gap Events in Hadronic Z Decays with L3 detector [PDF]

, 2001
Rapidity gaps have been studied in well separated completely symmetric 3 jet events from hadronic Z decays to search for colour singlet exchange. Asymmetries in particle flow and angular separation, defined with respect to the inter-jet regions, are ...
Banerjee, Swagato
core   +2 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source