Results 211 to 220 of about 418,106 (264)

Epigenetic editing of the STAT5B promoter attenuates milk nutrient loss in a bovine mastitis cell model. [PDF]

Protein Cell
Li S, Li X, Liu Q, Miao Y, Kang L, Jiang F.   +5 more
europepmc   +1 more source

Natural Frequencies of Levodopa‐Induced Dyskinesia in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Abnormal involuntary movements, known as dyskinesias, are common complications of levodopa treatment in patients with Parkinson's disease and can significantly impair quality of life. The underlying pathophysiology remains unclear, and current therapeutic options are limited.
Ioannis U. Isaias, Federica Avantaggiato, Gianni Pezzoli, Andrea Canessa   +3 more
wiley   +1 more source

From pineal photoreception to optogenetics: functional colour opponency based on a pineal bistable opsin. [PDF]

Eye Vis (Lond)
Wada S, Kawano-Yamashita E, Koyanagi M, Terakita A.   +3 more
europepmc   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian, Minghui Zhao, Yuanbo Hu, Kaiyue Wang, Haiguang Liu, Zetong Bai, Kebin Zheng   +6 more
wiley   +1 more source

Generative modelling of continuous feature foraging reveals probabilistic representations of target distributions. [PDF]

Atten Percept Psychophys
Fuller JCM, Kristjánsson Á, Clarke A, Ásgeirsson ÁG.   +3 more
europepmc   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Proteomic analysis of the eating quality of humped cattle beef from Rikaze cattle under various cooking methods. [PDF]

Food Chem X
Zheng H, Zhao X, Li J, Wang P, Li S, Li L, Liu Z.   +6 more
europepmc   +1 more source

Skin Colour Does Not Define Ethnicity: Quantifying Variation and Overlap Across Diverse Populations. [PDF]

Skin Res Technol
Lu Y, Xiao K, Li C, Pointer M.
europepmc   +1 more source

Correction: Colour of medicines and children's acceptability: What children think of the colour of oral dosage forms? [PDF]

Front Drug Deliv
Frontiers Production Office.
europepmc   +1 more source

Occupational exposure at petrol stations and red- green colour vision deficiency: a case-control study from Sudan. [PDF]

BMC Public Health
Ali IA, Ahmedelbashir Abdelrahman S, Magzoub AA.   +2 more
europepmc   +1 more source