Results 91 to 100 of about 451,802 (301)
A hybrid column generation algorithm based on metaheuristic optimization
Transport, 2016 The exact solution and heuristic solution have their own strengths and weaknesses on solving the Vehicle Routing Problems with Time Windows (VRPTW).
Wenbin Hu +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Effect of surfactants on liquid side mass transfer coefficients [PDF]
, 2005 In the present paper, the effect of liquid properties (surfactants) on bubble generation phenomenon, interfacial area and liquid side mass transfer coefficient was investigated.
Hebrard, Gilles +4 more
core +1 more source
Dynamic Generation of Cutting Patterns in Sawmills for Sustainable Planning
MathematicsThis study proposes two optimization models and a column-generation algorithm, applied at the root node, to support tactical planning in sawmills by dynamically generating log cutting patterns aligned with sustainability and efficiency objectives ...
Jorge Félix Mena-Reyes +3 more
doaj +1 more source
Speeding up column generation for robust wireless network planning
EURO Journal on Computational Optimization, 2013 The wireless network planning problem consists of base station placement and traffic node assignment to base stations. To incorporate traffic demand uncertainties, we follow the Γ-robustness approach by Bertsimas and Sim.
Grit Claßen +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Vectorwise: Beyond Column Stores
, 2012 This paper tells the story of Vectorwise, a high-performance analytical database system, from multiple perspectives: its history from academic project to commercial product, the evolution of its technical architecture, customer reactions to the product ...
Zukowski, Marcin +6 more
core
Column Generation based Primal Heuristics
, 2010 International audienceIn the past decade, significant progress has been achieved in developing generic primal heuristics that made their way into commercial mixed integer programming (MIP) solver. Extensions to the context of a column generation solution
C. Joncour +9 more
core +1 more source
EURO Journal on Computational Optimization, 2018 Many practical combinatorial optimization problems can be described by integer linear programs having an exponential number of variables, and they are efficiently solved by column generation algorithms.
Christian Artigues +2 more
doaj +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source