Results 101 to 110 of about 3,531,799 (287)

Column research council: proceedings 1969

, 1969
One of the purposes of the Council is to maintain a forum where problems related to the design and behavior of columns and other compression elements in metal structures can be presented for evaluation and discussion.
Column Research Council
core   +1 more source

Column generation algorithms for bi-objective combinatorial optimization problems with a min–max objective

EURO Journal on Computational Optimization, 2018
Many practical combinatorial optimization problems can be described by integer linear programs having an exponential number of variables, and they are efficiently solved by column generation algorithms.
Christian Artigues, Nicolas Jozefowiez, BoaduM. Sarpong   +2 more
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

FEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli, Carlotta Chiesa, Maher Abou Hachem, Ditte Hededam Welner   +3 more
wiley   +1 more source

Reformulation and decomposition of integer programs [PDF]

In this survey we examine ways to reformulate integer and mixed integer programs. Typically, but not exclusively, one reformulates so as to obtain stronger linear programming relaxations, and hence better bounds for use in a branch-and-bound based ...
WOLSEY , Laurence, VANDERBECK  , François   +1 more
core  

Annealing-Assisted Column Generation for Inequality-Constrained Combinatorial Optimization Problems

IEEE Access
Ising machines are expected to solve combinatorial optimization problems faster than the existing integer programming solvers. These problems, particularly those encountered in practical situations, typically involve inequality constraints.
Hiroshi Kanai, Masashi Yamashita, Kotaro Tanahashi, Shu Tanaka   +3 more
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Gas hold-up and bubble diameters in a gassed oscillatory baffled column [PDF]

, 2001
In this paper attempts are made to address how bubble behaviour in a batch oscillatory ba'ed column (OBC) contributes to the overall measured enhancement in mass transfer.
Ni, X., Ni, Xiongwei; id_orcid, Oliveira, Monica, Oliveira, M S N, Ni, Xiong-Wei; id_orcid, Oliveira, M. S N, Ni, X.; id_orcid   +6 more
core   +1 more source

A Vehicle Routing Problem Based on a Long-Distance Transportation Network with an Exact Optimization Algorithm

Mathematics
In vehicle routing problems, long-distance transportation poses a significant challenge to the optimization of transportation costs while adhering to regulations.
Toygar Emre, Rızvan Erol
doaj   +1 more source