Results 71 to 80 of about 835,149 (319)
El Llegat de Galton, Pearson, Fréchet i d'altres: com mesurar i interpretar l'associació estadística [PDF]
Presentem en tres parts els conceptes de correlació i d'associació estadística, començant per la noció de correlació de Galton, millorada per Pearson. Utilitzem com a il.lustració les dades clàssiques de Galton i Pearson sobre heretabilitat de pares i ...
Cuadras, Carles M.
core
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Developing countries can adapt to climate change effectively using nature-based solutions
Evidence on the effectiveness of climate change adaptation interventions in low- and middle-income countries has been rapidly growing in recent years, particularly in the agricultural and coastal sectors.
Sergio Villamayor-Tomas +7 more
doaj +1 more source
Emerging role of ARHGAP29 in melanoma cell phenotype switching
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
La construcció dels espais de la bibliofília en l’articulisme de Joan Francesc Mira
Resum: La biblioteca ha estat un àmbit que ha fascinat l’ésser humà a causa dels diferents nivells interpretatius que aquest espai genera. Aquest treball revisa els assajos periodístics en què l’escriptor Joan Francesc Mira s’hi refereix a fi d’il ...
Sergi Serra Adsuara
doaj
El text forma part dels materials docents programats mitjançant l'ajut del Servei de Política Lingüística de la Universitat de València.Temes per l'estudi de les tècniques de separació més rellevants.
Ramis Ramos, Guillermo
core
AbstractColumn chromatography is used extensively in nucleic acid chemistry to purify or characterize products from chemical reactions. This appendix focuses on separations using silica gel or alumina. The procedures described include loading the column, assembling the apparatus, separating compounds and collecting fractions, and optimizing ...
openaire +3 more sources
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source

