Results 71 to 80 of about 835,149 (319)

El Llegat de Galton, Pearson, Fréchet i d'altres: com mesurar i interpretar l'associació estadística [PDF]

open access: yes, 2015
Presentem en tres parts els conceptes de correlació i d'associació estadística, començant per la noció de correlació de Galton, millorada per Pearson. Utilitzem com a il.lustració les dades clàssiques de Galton i Pearson sobre heretabilitat de pares i ...
Cuadras, Carles M.
core  

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Developing countries can adapt to climate change effectively using nature-based solutions

open access: yesCommunications Earth & Environment
Evidence on the effectiveness of climate change adaptation interventions in low- and middle-income countries has been rapidly growing in recent years, particularly in the agricultural and coastal sectors.
Sergio Villamayor-Tomas   +7 more
doaj   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

La construcció dels espais de la bibliofília en l’articulisme de Joan Francesc Mira

open access: yesCultura, Lenguaje y Representación, 2017
Resum: La biblioteca ha estat un àmbit que ha fascinat l’ésser humà a causa dels diferents nivells interpretatius que aquest espai genera. Aquest treball revisa els assajos periodístics en què l’escriptor Joan Francesc Mira s’hi refereix a fi d’il ...
Sergi Serra Adsuara
doaj  

Tècniques de separació [PDF]

open access: yes, 2013
El text forma part dels materials docents programats mitjançant l'ajut del Servei de Política Lingüística de la Universitat de València.Temes per l'estudi de les tècniques de separació més rellevants.
Ramis Ramos, Guillermo
core  

Column Chromatography [PDF]

open access: yesCurrent Protocols in Nucleic Acid Chemistry, 2000
AbstractColumn chromatography is used extensively in nucleic acid chemistry to purify or characterize products from chemical reactions. This appendix focuses on separations using silica gel or alumina. The procedures described include loading the column, assembling the apparatus, separating compounds and collecting fractions, and optimizing ...
openaire   +3 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Home - About - Disclaimer - Privacy