Results 301 to 310 of about 1,058,395 (336)

Bacteriophages and viruses as a support for organic synthesis and combinatorial chemistry.

ACS Chemical Biology, 2012
Display of polypeptide on the coat proteins of bacteriophages and viruses is a powerful tool for selection and amplification of libraries of great diversity.
S. Ng, M. Jafari, R. Derda
semanticscholar   +1 more source

Diketopiperazines in Peptide and Combinatorial Chemistry

ChemInform, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
openaire   +4 more sources

Patenting of combinatorial chemistry

Expert Opinion on Therapeutic Patents, 1999
This article is a preview of an analysis, appearing shortly in Current Trends in Pharmaceutical Discovery entitled ‘Patenting of combinatorial chemistry’, which is a detailed analysis of patenting trends in the field of combinatorial chemistry from 1990 - 1998. In less than a decade, combinatorial chemistry has gone from a curiosity, to a subject which
Peter Steele, Lynsey Mulligan
openaire   +2 more sources

Discovery of linear receptors for multiple dihydrogen phosphate ions using dynamic combinatorial chemistry.

Journal of the American Chemical Society, 2011
We describe the use of dynamic combinatorial chemistry to discover a new series of linear hydrazone-based receptors that bind multiple dihydrogen phosphate ions.
Sophie R. Beeren, J. Sanders
semanticscholar   +1 more source

Integrating virtual screening and combinatorial chemistry for accelerated drug discovery.

Combinatorial chemistry & high throughput screening, 2011
Virtual screening is increasingly being used in drug discovery programs with a growing number of successful applications. Experimental methodologies developed to speed up the drug discovery processes include high-throughput screening and combinatorial ...
Fabian López-Vallejo, T. Caulfield, K. Martínez-Mayorga, M. Giulianotti, A. Nefzi, R. Houghten, J. Medina-Franco   +6 more
semanticscholar   +1 more source

The rise, fall and reinvention of combinatorial chemistry.

Chemical Communications, 2011
Combinatorial chemistry provides a powerful tool for the rapid creation of large numbers of synthetic compounds. Ideally, these libraries should be a rich source of bioactive molecules, but there is the general feeling that the initial promise of ...
T. Kodadek
semanticscholar   +1 more source

Photoinversion of sulfoxides as a source of diversity in dynamic combinatorial chemistry.

Organic Letters, 2011
Photochemical interconversion of the two diastereoisomers cis- and trans-thianthrene dioxide (1) can be considered an example of photodynamic combinatorial chemistry (PDCC) in which the interconversion among diastereomeric equilibrating species is ...
S. Di Stefano, Marco Mazzonna, E. Bodo, L. Mandolini, O. Lanzalunga   +4 more
semanticscholar   +1 more source

Organopalladium Reactions in Combinatorial Chemistry

ChemInform, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
Bräse, S., Köbberling, J., Griebenow, N.   +2 more
openaire   +2 more sources

Combinatorial chemistry: 20 years on…

Drug Discovery Today, 2002
Abstract ‘The mass of a protein library...would exceed that of the universe by more than two hundred orders of magnitude.’
openaire   +3 more sources

Dynamic Combinatorial Chemistry

2010
This long-awaited first book on this exciting new field in organic and supramolecular chemistry explains the fundamentals as well as possible applications of DCC. Authored by the Who's Who of DCC it spans the whole range of topics: catalysts, sensors, polymers, ligands, receptors, concluding with a look at future developments and perspectives.
Reek, Joost N.H., Otto, Sijbren
openaire   +2 more sources