Results 1 to 10 of about 1,178,819 (347)

Dielectrophoretic bead-droplet reactor for solid-phase synthesis [PDF]

Nature Communications
Solid-phase synthesis underpins many advances in synthetic and combinatorial chemistry, biology, and material science. The immobilization of a reacting species on the solid support makes interfacing of reagents an important challenge in this approach. In
Punnag Padhy, Mohammad Asif Zaman, Michael Anthony Jensen, Yao-Te Cheng, Yogi Huang, Mo Wu, Ludwig Galambos, Ronald Wayne Davis, Lambertus Hesselink   +8 more
doaj   +2 more sources

The Facile Solid-Phase Synthesis of Thiazolo-Pyrimidinone Derivatives [PDF]

Molecules
A thiazolo-pyrimidinone derivative library was developed through a facile solid-phase synthesis method. For the reaction, the thiazolo[4,5-d]pyrimidin-7(6H)-one structure was synthesized through efficient Thorpe–Ziegler and cyclization reactions.
Shuanghui Hua, Jimin Moon, Taeho Lee
doaj   +2 more sources

Solid-Phase Synthesis of Lipidated Peptides [PDF]

Angewandte Chemie - International Edition, 2004
Solid-phase synthesis of lipidated ...
Göran Kragol, José M Palomo, Herbert Waldmann   +2 more
exaly   +6 more sources

Heterocycles as a Peptidomimetic Scaffold: Solid-Phase Synthesis Strategies

Pharmaceuticals, 2021
Peptidomimetics are a privileged class of pharmacophores that exhibit improved physicochemical and biological properties. Solid-phase synthesis is a powerful tool for gaining rapid access to libraries of molecules from small molecules to biopolymers and ...
Aizhan Abdildinova, Mark J. Kurth, Young-Dae Gong   +2 more
doaj   +1 more source

The interplay between thermodynamics and kinetics in the solid-state synthesis of layered oxides. [PDF]

, 2020
In the synthesis of inorganic materials, reactions often yield non-equilibrium kinetic byproducts instead of the thermodynamic equilibrium phase. Understanding the competition between thermodynamics and kinetics is a fundamental step towards the rational
Bai, Jianming, Bianchini, Matteo, Ceder, Gerbrand, Clément, Raphaële J, Kim, Haegyeom, Kitchaev, Daniil, Ouyang, Bin, Shi, Tan, Sun, Wenhao, Wang, Feng, Wang, Jingyang, Wang, Yan, Xiao, Penghao, Zhang, Mingjian, Zhang, Yaqian   +14 more
core   +1 more source

Efficient Syntheses of 1,2,3-Triazoloamide Derivatives Using Solid- and Solution-Phase Synthetic Approaches

Molecules, 2015
Efficient synthetic routes for the preparation of secondary and tertiary 1,2,3-triazoloamide derivatives were developed. A secondary α-1,2,3-triazoloamide library was constructed and expanded by a previously developed solid-phase synthetic route and a ...
Doohyun Lee, Daehun Kim, Seungyeon Lee, Taegeum Kim, Joobin Kim, Sohee Kim, Kwang-Hyeon Liu, Sangkyu Lee, Jong-Sup Bae, Kyung-Sik Song, Chang-Woo Cho, Youn Kyung Son, Dong Jae Baek, Taeho Lee   +13 more
doaj   +1 more source

Fragment synthesis of disulfide-containing peptides

MethodsX, 2020
A new strategy for solid phase peptide synthesis in the fragment synthesis based on the use of 2-Cl-trityl resin as carrier to obtain protected peptide-resin and Rink Amide Resin, HOBT/HBTU or PyBOP/DIPEA or HATU/DIPEA as the coupling method is described.
Yuxuan Dai, Na Yue, Wenlong Huang, Hai Qian   +3 more
doaj   +1 more source

Effect of synthesis conditions on formation pathways of metal organic framework (MOF-5) Crystals [PDF]

, 2013
Metal Organic Frameworks (MOFs) represent a class of nanoporous crystalline materials with far reaching potential in gas storage, catalysis, and medical devices.
A. D. C. Burrows K., Ashleigh J. Fletcher, Biemmi E., Calleja G., Chen B., Chung S. Y., Colin McKinstry, Czaja A. U., Edmund J. Cussen, Farha O. K., Hermes S., Jan Sefcik, Kaye S. S., Li H., Li J. P., Liu Y. Y., Ma M., Rosi N. L., S. W. Hausdorf J., Sabouni R., Saha D., Saha D., Saha D. P., Saha D. P. D., Siddharth V. Patwardhan, Threlfall T., Tomic E. A., Wang Z. Q., Yoo Y., Zhao Z. X.   +29 more
core   +1 more source

Temperature Dependent Piezoelectric Properties of Lead-Free (1-x)K0.6Na0.4NbO3–xBiFeO3 Ceramics [PDF]

, 2020
(1-x)K0.4Na0.6NbO3–xBiFeO3 lead-free piezoelectric ceramics were successfully prepared in a single perovskite phase using the conventional solid-state synthesis.
Feteira, Antonio, Hussain, Fayaz, Khesro, Amir, Muhammad, Raz, Reaney, Ian M., Wang, Dawei, Wang, Ge   +6 more
core   +3 more sources

Solid-Phase Synthesis of Megamolecules

Journal of the American Chemical Society, 2020
This paper presents a solid-phase strategy to efficiently assemble multiprotein scaffolds-known as megamolecules-without the need for protecting groups and with precisely defined nanoscale architectures. The megamolecules are assembled through sequential reactions of linkers that present irreversible inhibitors for enzymes and fusion proteins ...
Blaise R. Kimmel, Justin A. Modica, Kelly Parker, Vinayak Dravid, Milan Mrksich   +4 more
openaire   +3 more sources