Results 21 to 30 of about 384,812 (159)

Optimized Solid Phase-Assisted Synthesis of Dendrons Applicable as Scaffolds for Radiolabeled Bioactive Multivalent Compounds Intended for Molecular Imaging

open access: yesMolecules, 2014
Dendritic structures, being highly homogeneous and symmetric, represent ideal scaffolds for the multimerization of bioactive molecules and thus enable the synthesis of compounds of high valency which are e.g., applicable in radiolabeled form as ...
Gabriel Fischer   +2 more
doaj   +1 more source

An overview of recent progress in modern synthetic approach—combinatorial synthesis

open access: yesBeni-Suef University Journal of Basic and Applied Sciences, 2020
Background In recent times, a powerful tool of combinatorial synthesis has been used for the preparation of large chemical entities through a small set up of reactions between different building blocks using solid-phase and solution-phase techniques ...
Chandravadivelu Gopi   +3 more
doaj   +1 more source

Rhodiasolv PolarClean – a greener alternative in solid-phase peptide synthesis

open access: yesGreen Chemistry Letters and Reviews, 2021
PolarClean, a green solvent prepared through the valorization of a byproduct of Nylon-66 manufacturing, shows an excellent capacity to dissolve all Fmoc-amino acids and key coupling reagents and additives.
Ashish Kumar   +3 more
doaj   +1 more source

Magnetic nanoparticle-based solid phase peptide synthesis and the synchronous detection of their biological activity

open access: yesMaterials Today Advances, 2021
The solid-phase peptide synthesis (SPPS) strategy, as the main procedure of peptide manufacturing, has a profound impact on the research of peptides.
D. Luo   +8 more
doaj   +1 more source

Novel Solution- and Solid-Phase Syntheses of Heterocyclic Systems

open access: yesCHIMIA, 2003
Heterocyclic compounds are an attractive source of screening library structures because they possess varied structural diversity and can exhibit potent biological activity.
Gaelle Cabon   +4 more
doaj   +1 more source

Mechanochemical synthesis of AlCoCrFeNi powders via high-energy ball milling

open access: yesҚарағанды университетінің хабаршысы. Физика сериясы, 2023
AlCoCrFeNi powders in equimolar ratios were synthesized by mechanochemical synthesis on a high-energy ball milling machine (HEBM). The elemental and phase composition of AlCoCrFeNi powders before and after mechanochemical synthesis were investigated by ...
Е.Е. Камбаров   +3 more
doaj   +1 more source

Organic Synthesis on Solid Phase. (Supports, Linkers, Reactions)

open access: yesMolecules, 2001
n ...
Florencio Zaragoza Dörwald
doaj   +1 more source

Novel Solution- and Solid-Phase Strategies for the Parallel and Combinatorial Synthesis of Small-Molecular-Weight Compound Libraries

open access: yesCHIMIA, 1996
In this account dedicated to '100 years Roche' in CHIMIA, we present some of our strategies towards the synthesis of interesting novel amino-acid-derived building blocks; multigeneration synthesis of thiazole libraries in solution; a novel solid-
Alexander Chucholowski   +4 more
doaj   +2 more sources

Total Synthesis of Cyclosenegalin A

open access: yesChemistryOpen
A Pro‐Gly‐typed cyclopeptide, cyclosenegalin A, was firstly isolated from Annona senegalensis and Annona scleroderma. In this study, we reported synthesis the cycloheptapeptide with a combination of solid‐ and solution‐phase synthetic methods. This study
Anderson Arnold Aloanis   +3 more
doaj   +1 more source

Solid Phase Synthesis of a Metronidazole Oligonucleotide Conjugate

open access: yesMolecules, 2006
Direct, solid phase synthesis of an oligonucleotide conjugate of the antibioticdrug metronidazole was accomplished by the phosphoramidite method. Removal ofprotecting groups and cleavage from the controlled pore glass (CPG) solid support wassuccessful ...
William Fraser   +2 more
doaj   +1 more source

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