Results 31 to 40 of about 384,812 (159)

Practical Protocols for Solid-Phase Peptide Synthesis 4.0

open access: yesMethods and Protocols, 2022
According to the Food and Drug Administration (FDA), there are two kinds of drugs, namely New Chemical Entities (NCEs) and Biologics [...]
Beatriz G. de la Torre   +1 more
doaj   +1 more source

Introducing azobenzenes as solid phase peptide synthesis linkers [PDF]

open access: yesRSC Chemical Biology
Orthogonally cleavable linkers are essential tools in solid-phase peptide synthesis (SPPS). We present a fluorogenic C̲o̲umarin-L̲oaded A̲z̲obenzene (COLAZ) linker for SPPS, which offers base and acid stability and a mild reductive cleavage.
Connor B. Śmieja   +5 more
doaj   +1 more source

SASRIN™ a Versatile Tool in Peptide Synthesis and Solid-Phase Organic Chemistry

open access: yesCHIMIA, 1999
The synthesis of the 4-(3-methoxy-4-(hydroxymethyl)phenoxymethyl) derivative of polystyrene-co-divinylbenzene (SASRIN™), its derivatives and its application in solid-phase peptide synthesis will be briefly reviewed in this paper.
Monika Mergler   +4 more
doaj  

Laser solid-phase synthesis of single-atom catalysts

open access: yesLight: Science & Applications, 2021
Synthesis of Pt single atom catalysts is achieved by one-step laser irradiation of “isolated” H2PtCl6 precursor on graphene oxide, via filtration and freeze-drying sublimation, by simultaneous pyrolysis of the precursor and reduction of graphene oxide.
Yudong Peng   +5 more
doaj   +1 more source

Solid‐Phase Supports for Oligonucleotide Synthesis [PDF]

open access: yesCurrent Protocols in Nucleic Acid Chemistry, 2000
AbstractThis unit begins with a discussion of the advantages and disadvantages of oligonucleotide synthesis using solid supports. The physical and chemical properties of solid‐phase supports are discussed in terms of their suitability for oligonucleotide synthesis. In addition, the unit outlines the properties of linkers used for transient or permanent
openaire   +4 more sources

Synthèse de molécules d'intérêt biologique. Contribution à la synthèse des bastadines [PDF]

open access: yesBiotechnologie, Agronomie, Société et Environnement, 2010
Synthesis of molecules of biological interest. Contribution to the synthesis of bastadins. The metabolites are a biochemical area whose interest is in constant progression.
Decamps, C.   +4 more
doaj  

Solid Phase Formylation of N-Terminus Peptides

open access: yesMolecules, 2016
Formylation of amino groups is a critical reaction involved in several biological processes including post-translational modification of histones. The addition of a formyl group (CHO) to the N-terminal end of a peptide chain generates biologically active
Anna Lucia Tornesello   +2 more
doaj   +1 more source

Fast Method for Synthesis of Alkyl and Aryl-N-Methylnitrones

open access: yesMolecules, 2011
A simple, fast, efficient and eco-friendly procedure was developed for the synthesis of alkyl and aryl-N-methylnitrones. The corresponding nitrones of aromatic aldehydes, aliphatic aldehydes and alicyclic carbonyl compounds were prepared from N ...
Yilmaz Yildirir   +3 more
doaj   +1 more source

The effect of solvent on reactivity of the Li2S–P2S5 system in liquid-phase synthesis of Li7P3S11 solid electrolyte

open access: yesScientific Reports, 2021
Synthesis technology for sulfide-based solid electrolytes based on liquid-phase processing has attracted significant interest in relation to achieving the optimal design for all-solid-state batteries.
Hirotada Gamo   +2 more
doaj   +1 more source

TiO2 phase-controlled synthesis of Li-La-TiO solid electrolytes for advanced all-solid-state batteries

open access: yesJournal of Asian Ceramic Societies
This study focused on achieving high ionic conductivity in Li-La-TiO (LLTO) solid electrolyte. To enhance ionic conductivity, the synthesis reaction was optimized by controlling the composite crystal structure of TiO2 at the B-site of the perovskite ...
Minjeong Kim   +11 more
doaj   +1 more source

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