Results 1 to 10 of about 172,692 (298)

One-Pot Parallel Synthesis of Unclosed CryptandsSearching for Selective Anion Receptors via Static Combinatorial Chemistry Techniques [PDF]

open access: goldACS Omega, 2020
We present the synthesis of 17 macrocyclic compounds having the structure of so-called unclosed cryptands, acting as anion receptors. These compounds possess amide functions playing the role of hydrogen-bond-donating systems. We have synthesized the presented compounds both by standard methods (using batch conditions) and by static combinatorial ...
Patryk Niedbała, Janusz Jurczak
doaj   +7 more sources

Novel Screening Technique: Integrated Combinatorial Green Chemistry & Life Cycle Analysis (CGC-LCA)

open access: goldBioResources, 2013
The integration of combinatorial green chemistry (CGC), a more benign approach to combinatorial chemistry, with environmental life cycle assessment (LCA) methodologies as an improved process development methodology is discussed. It is expected that the CGC approach will require less labor and result in more globally optimized assay results, leading to ...
Carter Reeb   +2 more
openalex   +5 more sources

DNA display II. Genetic manipulation of combinatorial chemistry libraries for small-molecule evolution.

open access: yesPLoS Biology, 2004
Biological in vitro selection techniques, such as RNA aptamer methods and mRNA display, have proven to be powerful approaches for engineering molecules with novel functions.
David R Halpin, Pehr B Harbury
doaj   +2 more sources

Old and Modern Antibiotic Structures with Potential for Today’s Infections

open access: yesADMET and DMPK, 2022
Due to the lack of new antibiotics with efficacy against the ESKAPE and other resistant microbes, coupled to the demise of major pharmaceutical company antibiotic discovery programs, due to a number of factors but mainly ROI calculations and the lack of ...
David Newman
doaj   +1 more source

Combinatorial Design of Novel Multiprincipal Element Alloys Using Experimental Techniques

open access: yesAdvanced Engineering Materials, 2023
Multiprincipal element alloys (MPEAs) including high‐entropy alloys are in the focus of materials science since many MPEA compositions exhibit outstanding mechanical and physical properties.
J. Gubicza
semanticscholar   +1 more source

Exploring chemical space and structural diversity of supramolecular peptide materials

open access: yesSupramolecular Materials, 2023
Searching chemical space and expanding the structural diversity of supramolecular self-assembly based on the development of combinatorial libraries is significant to the guided design of bio-inspired materials.
Mengyue Zhu, Jing Chen, Yiyang Lin
doaj   +1 more source

Modeling Intercalation Chemistry with Multiredox Reactions by Sparse Lattice Models in Disordered Rocksalt Cathodes [PDF]

open access: yesPRX Energy, 2023
Modern battery materials can contain many elements with substantial site disorder, and their configurational state has been shown to be critical for their performance.
Peichen Zhong   +4 more
semanticscholar   +1 more source

Improved Topical Drug Delivery: Role of Permeation Enhancers and Advanced Approaches

open access: yesPharmaceutics, 2022
The delivery of drugs via transdermal routes is an attractive approach due to ease of administration, bypassing of the first-pass metabolism, and the large skin surface area.
Victor Hmingthansanga   +5 more
doaj   +1 more source

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