One-Pot Parallel Synthesis of Unclosed CryptandsSearching for Selective Anion Receptors via Static Combinatorial Chemistry Techniques [PDF]
We present the synthesis of 17 macrocyclic compounds having the structure of so-called unclosed cryptands, acting as anion receptors. These compounds possess amide functions playing the role of hydrogen-bond-donating systems. We have synthesized the presented compounds both by standard methods (using batch conditions) and by static combinatorial ...
Patryk Niedbała, Janusz Jurczak
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Novel Screening Technique: Integrated Combinatorial Green Chemistry & Life Cycle Analysis (CGC-LCA)
The integration of combinatorial green chemistry (CGC), a more benign approach to combinatorial chemistry, with environmental life cycle assessment (LCA) methodologies as an improved process development methodology is discussed. It is expected that the CGC approach will require less labor and result in more globally optimized assay results, leading to ...
Carter Reeb+2 more
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Biological in vitro selection techniques, such as RNA aptamer methods and mRNA display, have proven to be powerful approaches for engineering molecules with novel functions.
David R Halpin, Pehr B Harbury
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Buchbesprechung: Analytical Techniques in Combinatorial Chemistry. Von Michael E. Swartz. [PDF]
Jörg W. Metzger
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Molecular Modeling, Computational/ Combinatorial Chemistry, and Chemical Diversity: Methods and Techniques [PDF]
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Old and Modern Antibiotic Structures with Potential for Today’s Infections
Due to the lack of new antibiotics with efficacy against the ESKAPE and other resistant microbes, coupled to the demise of major pharmaceutical company antibiotic discovery programs, due to a number of factors but mainly ROI calculations and the lack of ...
David Newman
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Combinatorial Design of Novel Multiprincipal Element Alloys Using Experimental Techniques
Multiprincipal element alloys (MPEAs) including high‐entropy alloys are in the focus of materials science since many MPEA compositions exhibit outstanding mechanical and physical properties.
J. Gubicza
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Exploring chemical space and structural diversity of supramolecular peptide materials
Searching chemical space and expanding the structural diversity of supramolecular self-assembly based on the development of combinatorial libraries is significant to the guided design of bio-inspired materials.
Mengyue Zhu, Jing Chen, Yiyang Lin
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Modeling Intercalation Chemistry with Multiredox Reactions by Sparse Lattice Models in Disordered Rocksalt Cathodes [PDF]
Modern battery materials can contain many elements with substantial site disorder, and their configurational state has been shown to be critical for their performance.
Peichen Zhong+4 more
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Improved Topical Drug Delivery: Role of Permeation Enhancers and Advanced Approaches
The delivery of drugs via transdermal routes is an attractive approach due to ease of administration, bypassing of the first-pass metabolism, and the large skin surface area.
Victor Hmingthansanga+5 more
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