High-throughput in-situ characterization and modelling of precipitation kinetics in compositionally graded alloys [PDF]
, 2015 The development of new engineering alloy chemistries is a time consuming and iterative process. A necessary step is characterization of the nano/microstructure to provide a link between the processing and properties of each alloy chemistry considered.
De Geuser, F. +3 more
arxiv +5 more sources
Improved Topical Drug Delivery: Role of Permeation Enhancers and Advanced Approaches
Pharmaceutics, 2022 The delivery of drugs via transdermal routes is an attractive approach due to ease of administration, bypassing of the first-pass metabolism, and the large skin surface area.
Victor Hmingthansanga +5 more
doaj +1 more source
Chimeric rhinoviruses displaying MPER epitopes elicit anti-HIV neutralizing responses. [PDF]
PLoS ONE, 2013 The development of an effective AIDS vaccine has been a formidable task, but remains a critical necessity. The well conserved membrane-proximal external region (MPER) of the HIV-1 gp41 glycoprotein is one of the crucial targets for AIDS vaccine ...
Guohua Yi +11 more
doaj +1 more source
Development of Advanced Macrosphelides: Potent Anticancer Agents
Molecules, 2015 Synthetic approaches to macrosphelide derivatives, based on medicinal chemistry, are summarized. This review contains conventional medicinal chemistry approaches, combinatorial chemistry, fluorous tagging techniques and affinity chromatography ...
Seung-Mann Paek
doaj +1 more source
Combinatorial structures to modeling simple games and applications [PDF]
, 2017 We connect three different topics: combinatorial structures, game theory and chemistry. In particular, we establish the bases to represent some simple games, defined as influence games, and molecules, defined from atoms, by using combinatorial structures.
Molinero Albareda, Xavier
core +1 more source
Combinatorial structures to construct simple games and molecules [PDF]
, 2017 We connect three different topics: combinatorial structures, game theory and chemistry. In particular, we establish the bases to represent some simple games, defined as influence games, and molecules, defined from atoms, by using ...
Molinero Albareda, Xavier
core +2 more sources
CHIMIA, 2003 This review aims at giving a short introduction to the most important areas of library design. The description of compounds by descriptors and fingerprints, and similarity-based clustering techniques are illustrated in the context of untargeted ...
Friederike Stoll
doaj +1 more source
Química Nova, 2005 Combinatorial chemistry refers to techniques to rapidly fabricate tens, hundreds or even thousands of different micro samples. The analysis of the large number of samples generated by combinatorial methods requires highly efficient analytical methods. In
Najla Maroun Estrada +3 more
doaj +1 more source
Similarity-based data mining in files of two-dimensional chemical structures using fingerprint measures of molecular resemblance [PDF]
, 2011 This paper reviews the use of measures of intermolecular similarity for processing databases of chemical structures, which play an important role in the discovery of new drugs by the pharmaceutical industry.
Willett, P.
core +1 more source
Visual and computational analysis of structure-activity relationships in high-throughput screening data [PDF]
, 2001 Novel analytic methods are required to assimilate the large volumes of structural and bioassay data generated by combinatorial chemistry and high-throughput screening programmes in the pharmaceutical and agrochemical industries. This paper reviews recent
Agrafiotis +75 more
core +1 more source