Results 141 to 150 of about 1,967,671 (302)

A Scala Embedded DSL for Combinatorial Optimization in Software Requirements Engineering [Elektronisk resurs]

open access: yes, 2013
The goal of the presented work is to provide support for software requirements engineering domain experts in modeling combinatorial optimization problems that arise in requirements prioritization and release planning.
Kuchcinski, Krzysztof,   +2 more
core  

Combinatorial Optimization with Competing Agents

open access: yes, 2016
This chapter deals with three specific studies conducted within the combinatorial optimization for competing agents (COCA) project. It also deals with optimization problems arising from the relationship between members of a social network.
Gourvès, Laurent   +4 more
core   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

Beyond Neural Solvers: A Critical Review of Machine Learning for Combinatorial Optimization

open access: yesMathematics
Combinatorial optimization is a key component in critical decision problems such as routing, scheduling, network design, and graph optimization. Although combinatorial optimization methods, including exact algorithms, approximation methods, constraint ...
Mostafa E. A. Ibrahim   +2 more
doaj   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

open access: yesFEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang   +10 more
wiley   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

open access: yesFEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo   +4 more
wiley   +1 more source

A general ant colony model to solve combinatorial optimization problems

open access: yesRevista Colombiana de Computación, 2001
An Ants System is an artificial system based on the behavior of real ant colonies, which is used to solve combinatorial problems. Keywords: Combinatorial Optimization Problem,AntSystem, the Graph Partitioning and The Traveling Salesman Problems.
José Aguilar
doaj  

Quantum-enhanced greedy combinatorial optimization solver. [PDF]

open access: yesSci Adv, 2023
Dupont M   +15 more
europepmc   +1 more source

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

open access: yesFEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda   +4 more
wiley   +1 more source

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