Results 141 to 150 of about 36,738 (263)

Combinatorial optimization by weight annealing in memristive hopfield networks. [PDF]

Sci Rep, 2021
Fahimi Z, Mahmoodi MR, Nili H, Polishchuk V, Strukov DB.   +4 more
europepmc   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Combinatorial optimization with Kerr solitons. [PDF]

Sci Adv
Jin Y, Chauhan N, Zang J, Edwards B, Chaudhari P, Aflatouni F, Papp SB.   +6 more
europepmc   +1 more source

Combinatorial Optimization of Activity-Based Probes for Acyl Protein Thioesterases 1 and 2. [PDF]

ACS Med Chem Lett, 2022
Vanhoutte R, Verhelst SHL.
europepmc   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Simplicity and Complexity in Combinatorial Optimization. [PDF]

Entropy (Basel)
Dingle K, Hutter M.
europepmc   +1 more source

Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics. [PDF]

Nat Commun, 2022
Leppek K, Byeon GW, Kladwang W, Wayment-Steele HK, Kerr CH, Xu AF, Kim DS, Topkar VV, Choe C, Rothschild D, Tiu GC, Wellington-Oguri R, Fujii K, Sharma E, Watkins AM, Nicol JJ, Romano J, Tunguz B, Diaz F, Cai H, Guo P, Wu J, Meng F, Shi S, Participants E, Dormitzer PR, Solórzano A, Barna M, Das R.   +28 more
europepmc   +1 more source

Intelligent Tutoring Systems for Adult Learning in STEM Disciplines

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley   +1 more source

DiSCO: deconvoluting spatial transcriptomics via combinatorial optimization with a foundational diffusion model. [PDF]

Brief Bioinform
Liu J, Wu Y, Li L.
europepmc   +1 more source

Multi-task dispatch of shared autonomous electric vehicles for Mobility-on-Demand services - combination of deep reinforcement learning and combinatorial optimization method. [PDF]

Heliyon, 2022
Wang N, Guo J.
europepmc   +1 more source