Results 61 to 70 of about 1,317,810 (296)

A Refinement of the Sylvester Problem: Probabilities of Combinatorial Types

open access: yesDiscrete & Computational Geometry
Abstract Let $$X_1,\ldots , X_{d+2}$$ X 1 ,
Zakhar Kabluchko, Hugo Panzo
openaire   +2 more sources

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

THE EXPECTED JAGGEDNESS OF ORDER IDEALS

open access: yesForum of Mathematics, Sigma, 2017
The jaggedness of an order ideal $I$ in a poset $P$ is the
MELODY CHAN   +3 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

SINGULARITY OF RANDOM SYMMETRIC MATRICES—A COMBINATORIAL APPROACH TO IMPROVED BOUNDS

open access: yesForum of Mathematics, Sigma, 2019
Let $M_{n}$ denote a random symmetric $n\times n$ matrix whose upper-diagonal entries are independent and identically distributed Bernoulli random variables (which take values $1$ and $-1$ with probability $1/2$ each). It is widely conjectured that $M_{n}
ASAF FERBER, VISHESH JAIN
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Numerous but rare: an exploration of magic squares. [PDF]

open access: yesPLoS ONE, 2015
How rare are magic squares? So far, the exact number of magic squares of order n is only known for n ≤ 5. For larger squares, we need statistical approaches for estimating the number.
Akimasa Kitajima, Macoto Kikuchi
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Study of Random Biased d-ary Tries Model

open access: yesپژوهش‌های ریاضی, 2016
Tries are the most popular data structure on strings. We can construct d-ary tries by using strings over an alphabet leading to d-ary tries. Throughout the paper we assume that strings stored in trie are generated by an appropriate memory less source. In
r kazemi, h. abdolahinohoji, s norouzi
doaj  

Combinatorial solid-phase synthesis of 4,6-diaryl and 4-aryl, 6-alkyl-1,3,5-triazines and their application to efficient biofuel production

open access: yes, 2012
10.1021/co300007aACS Combinatorial Science147395 ...
Kim, Jaoon Y. H.   +15 more
core   +1 more source

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