Results 51 to 60 of about 33,492 (302)
Bayesian nonparametric estimators derived from conditional Gibbs structures [PDF]
We consider discrete nonparametric priors which induce Gibbs-type exchangeable random partitions and investigate their posterior behavior in detail.
PRUENSTER, IGOR +5 more
core +1 more source
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
经典组合优化问题的概率极限定理(Probability limit theorems of classical combinatorial optimization problems)
A review was given of the principal probability limit theorems of solutions to classical combinatorial optimization problems.The emphasis was on the travelling salesman problems,minimal spanning trees,matching and lengths of the longest increasing ...
SUZhong-gen(苏中根)
doaj +1 more source
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Sampling with removal in LP-type problems
Random sampling is an important tool in optimization subject to finitely or infinitely many constraints. Here we are interested in obtaining solutions of low cost that violate only few constraints.
Bernd Gärtner
doaj +1 more source
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
A Combinatorial Auction for Collaborative Planning [PDF]
When rational, utility-maximizing agents encounter an opportunity to collaborate on a group activity they must determine whether to commit to that activity. We refer to this problem as the initial-commitment decision problem (ICDP). The paper describes a
Hunsberger, Luke, Grosz, Barbara
core +1 more source
In this paper, a new probability mechanism based particle swarm optimization (PMPSO) algorithm is proposed to solve combinatorial optimization problems.
Shuai Li +3 more
doaj +1 more source
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source

