Results 71 to 80 of about 33,492 (302)

Finitary approximations of free probability, involving combinatorial representation theory [PDF]

open access: yes, 2023
This thesis contributes to two theories which approximate free probability by finitary combinatorial structures. The first is finite free probability, which is concerned with expected characteristic polynomials of various random matrices and was ...
Campbell, Jacob
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Reasoning on transition from manipulative strategies to general procedures in solving counting problems [PDF]

open access: yes, 2010
We describe the procedures used by 11- to 12-year-old students for solving basic counting problems in order to analyse the transition from manipulative strategies involving direct counting to the use of the multiplication principle as a general procedure
Figueiras, Lourdes, Cañadas, María C.
core  

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

Study of Random Biased d-ary Tries Model

open access: yesپژوهش‌های ریاضی, 2016
Tries are the most popular data structure on strings. We can construct d-ary tries by using strings over an alphabet leading to d-ary tries. Throughout the paper we assume that strings stored in trie are generated by an appropriate memory less source. In
r kazemi, h. abdolahinohoji, s norouzi
doaj  

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Basic elements and problems of probability theory [PDF]

open access: yes, 1999
After a brief review of ontic and epistemic descriptions, and of subjective, logical and statistical interpretations of probability, we summarize the traditional axiomatization of calculus of probability in terms of Boolean algebras and its set ...
Primas, Hans, Hans Primas
core  

Distance-based exponential probability models on constrained combinatorial optimization problems [PDF]

open access: yes, 2018
Estimation of distribution algorithms have already demonstrated their utility when solving a broad range of combinatorial problems. However, there is still room for methodological improvements when approaching constrained type problems.
Lozano, J.A., Ceberio, J., Mendiburu, A.
core   +1 more source

Distribution of the combinatorial multisets component vectors

open access: yesLietuvos Matematikos Rinkinys, 2012
We explore a class of random combinatorial structures called weighted multisets. Their components are taken from an initial set satisfying general boundedness conditions posed on the number of elements with a given weight.
Eugenijus Manstavičius   +1 more
doaj   +1 more source

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