Results 171 to 180 of about 57,805 (348)

Primary cardiac T‐cell rich large B‐cell lymphoma causing aortic stenosis with metastasis in a Warmblood

open access: yesEquine Veterinary Education, EarlyView.
Summary An 18‐year‐old Warmblood mare was presented to the Royal Veterinary College Equine Referral Hospital for investigation of progressive periocular and facial swelling, weight loss and tachycardia. Physical examination additionally identified bilateral pansystolic (grade 5/6 basilar left‐sided, 2/6 right‐sided), cardiac murmurs, submandibular ...
S. E. Talbot   +4 more
wiley   +1 more source

Tailoring Targeted Therapy to Individual Patients: Lessons to be Learnt from the Development of Mitomycin C [PDF]

open access: yes, 2007
The modern era of targeted therapeutics offers the potential to tailor therapy to individual patients whose tumours express a specific target. Previous attempts to forecast tumour response to conventional chemotherapeutics based on similar principles ...
Phillips, Roger M, Volpato, Milene
core  

CDKL5 regulates the initiation of retrograde axonal transport through CLIP170–dynactin complex formation

open access: yesThe FEBS Journal, EarlyView.
Activation of CLIP170 by CDKL5 in wild‐type (WT) cells promotes its open conformation and association with tyrosinated microtubule (MT) plus‐ends (+), where it works as a docking site to recruit the dynactin–dynein–cargo complex, promoting the initiation of retrograde transport. In knock‐out (KO) neurons, CLIP170 is mainly present in a closed (inactive)
Serena Baldin   +4 more
wiley   +1 more source

Evaluation of DNA repair capacity in parents of pediatric patients diagnosed with autism spectrum disorder using the comet assay procedure. [PDF]

open access: yesIBRO Neurosci Rep, 2023
Akouchekian M   +5 more
europepmc   +1 more source

Older Adults' Self‐Care and Family Caregiver Contribution in Multiple Chronic Conditions: A Dyadic Qualitative Study

open access: yesJournal of Advanced Nursing, EarlyView.
ABSTRACT Aims To explore how older adult‐family caregiver dyads jointly manage multiple chronic conditions. Specifically, it investigates how dyads (i) prioritise chronic diseases, (ii) make and negotiate decisions related to self‐care and (iii) define and distribute self‐care tasks and caregiver contributions.
Giulia Andrea Baldan   +6 more
wiley   +1 more source

Evaluation of Imidacloprid Genotoxicity in Chrysoperla Externa Eggs (Neuroptera: Chrysopidae) Through Comet Assay

open access: green, 2023
Fernández Acevedo   +4 more
openalex   +1 more source

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