Results 41 to 50 of about 2,103,717 (319)

Planetary Science Goals for the Spitzer Warm Era [PDF]

open access: yes, 2007
The overarching goal of planetary astronomy is to deduce how the present collection of objects found in our Solar System were formed from the original material present in the proto-solar nebula.
B. Bhattacharya   +10 more
core   +2 more sources

SMAD4 Palmitoylation Drives a Metabolic‐Transcriptional Circuit to Promote Tumorigenesis and Confers Radiosensitivity in Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
This study identifies palmitoylation as a novel regulatory modification of SMAD4, mediated by ZDHHC22/APT2. It activates fatty acid synthesis, creating a self‐reinforcing SMAD4–FASN–palmitate feedback loop that drives pancreatic cancer growth and enhances radiotherapy sensitivity.
Yang Wang   +16 more
wiley   +1 more source

Down But Not Out: The Case of Long-period Comet C/2021 O3 (Panstarrs)

open access: yesThe Astronomical Journal
We combine ground- and space-based observations of long-period comet C/2021 O3 (Panstarrs; perihelion distance 0.287 au) in order to investigate its reported near-perihelion destruction.
David Jewitt   +3 more
doaj   +1 more source

Prevailing dust-transport directions on comet 67P/Churyumov-Gerasimenko

open access: yes, 2015
Dust transport and deposition behind larger boulders on the comet 67P/Churyumov-Gerasimenko (67P/C-G) have been observed by the Rosetta mission. We present a mechanism for dust transport vectors based on a homogenous surface activity model incorporating ...
Kramer, Tobias, Noack, Matthias
core   +1 more source

The Origins of Comets

open access: yesEos, Transactions American Geophysical Union, 1992
Do we live in astronomically disappointing times? Are the skies duller than they've been in the past‐comets less spectacular, meteors less frequent, and the zodiacal lights dimmer? Certainly as an amateur astronomer I have been haunted by that impression.
openaire   +1 more source

Inhibition of SIRT7 Overcomes Radioresistance in Pancreatic Neuroendocrine Tumors by Reactivating MEN1 Expression

open access: yesAdvanced Science, EarlyView.
Pancreatic neuroendocrine tumors frequently silence MEN1 through epigenetic mechanisms. Here, SIRT7 recruits DNMT1 to the MEN1 promoter, drives hypermethylation, and enhances DNA repair. Inhibiting SIRT7 restores MEN1, reduces MRN complex abundance, impairs double‐strand break repair, and sensitizes PanNET models to radiation, supporting SIRT7 as a ...
Jianyun Jiang   +11 more
wiley   +1 more source

The Ice Chemistry in Comets and Planet-forming Disks: Statistical Comparison of CH3OH, H2CO, and NH3 Abundance Ratios

open access: yesThe Astrophysical Journal Letters
Comets are frozen remnants of our solar system’s formation, and comparing their chemical composition to that of planet-forming systems can reveal crucial insights about our origins, potentially answering one of the most challenging questions in planetary
Manuela Lippi   +7 more
doaj   +1 more source

SOFIA Infrared Spectrophotometry of Comet C/2012 K1 (Pan-STARRS)

open access: yes, 2015
We present pre-perihelion infrared 8 to 31 micron spectrophotometric and imaging observations of comet C/2012 K1 (Pan-STARRS), a dynamically new Oort Cloud comet, conducted with NASA's Stratospheric Observatory for Infrared Astronomy (SOFIA) facility ...
de Pater, Imke   +10 more
core   +1 more source

1. The Origin of Comets [PDF]

open access: yesInternational Astronomical Union Colloquium, 1977
Empirical data are confronted with different hypotheses on the origin of comets. The hypotheses are classified into three categories: 1) Comets were condensed from the solar nebula and ejected later into the Oort’s cloud. 2) Comets were condensed in situ, more or less recently, on their present trajectories; 3) Reversing the arrow of time in the ...
openaire   +1 more source

A primordial origin for molecular oxygen in comets: a chemical kinetics study of the formation and survival of O2 ice from clouds to discs [PDF]

open access: yes, 2016
Molecular oxygen has been confirmed as the fourth most abundant molecule in cometary material (O2/H2O ∼ 4 per cent) and is thought to have a primordial nature, i.e. coming from the interstellar cloud from which our Solar system was formed.
V. Taquet   +3 more
semanticscholar   +1 more source

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