Results 11 to 20 of about 4,657 (224)

Assessing the genotoxicity of oral titanium dioxide nanoparticle administration in male rats using micronuclei and comet assay [PDF]

open access: yesFayoum Journal of Agricultural Research and Development, 2023
This study evaluated the toxic effects of titanium dioxide (TiO2) nanoparticles (NPs) on rats that received oral administration of TiO2-NPs with a particle size of 15±2nm once daily at doses of 0, 50, 100, 150, 200, and 300mg/kg for ten weeks.
Amal G. Ramadan   +3 more
doaj   +1 more source

Formin' a comet tail [PDF]

open access: yesNature Reviews Microbiology, 2010
Comet tail formation in Rickettsia spp. relies on the formin-like protein Sca2 to mediate actin nucleation.
openaire   +2 more sources

Estimation of the applied doses in irradiated anchovy and bluefish for shelf-life extension using image analysis in combination with DNA comet assay

open access: yesFood Materials Research, 2023
The objective of the present study was to estimate applied doses of irradiated anchovy (1.83−4.22 kGy) and bluefish (1.98−5.40 kGy) for shelf-life extension by using image analysis in combination with comet assay for trading irradiated fish, especially ...
Nurcan Cetinkaya   +5 more
doaj   +1 more source

Tails of Comets [PDF]

open access: yesNature, 1870
IN NATURE of 16th December, Prof. Tait advances the opinion that the tail of a comet consists of nothing but meteorites; mentioning in proof of this that the orbits of the August and November meteors have been determined, and found to be identical with those of two known comets. I do not question the importance of this most remarkable fact, but I think
openaire   +1 more source

Actin filament attachments for sustained motility in vitro are maintained by filament bundling. [PDF]

open access: yesPLoS ONE, 2012
We reconstructed cellular motility in vitro from individual proteins to investigate how actin filaments are organized at the leading edge. Using total internal reflection fluorescence microscopy of actin filaments, we tested how profilin, Arp2/3, and ...
Xiaohua Hu, Jeffrey R Kuhn
doaj   +1 more source

Standardizing electrophoresis conditions: how to eliminate a major source of error in the comet assay.

open access: yesFrontiers in Genetics, 2015
In the alkaline comet assay, cells are embedded in agarose, lysed, and then subjected to further processing including electrophoresis at high pH (>13). We observed very large variations of mean comet tail lengths of cell samples from the same population ...
Gunnar Brunborg
doaj   +1 more source

The Comet Assay: Tails of the (Un)expected. Use of the comet assay in pharmaceutical development.

open access: yesFrontiers in Genetics, 2015
In genotoxicity testing of pharmaceuticals the rodent alkaline comet assay is being increasingly used as a second in vivo assay in addition to the in vivo micronucleus assay to mitigate in vitro positive results as recommended by regulatory guidance.
Bas-jan Van Der Leede
doaj   +1 more source

The spectrin cytoskeleton is crucial for adherent and invasive bacterial pathogenesis. [PDF]

open access: yesPLoS ONE, 2011
Various enteric bacterial pathogens target the host cell cytoskeletal machinery as a crucial event in their pathogenesis. Despite thorough studies detailing strategies microbes use to exploit these components of the host cell, the role of the spectrin ...
Tyson Ruetz   +2 more
doaj   +1 more source

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