Results 21 to 30 of about 101,128 (273)

Standardizing electrophoresis conditions: how to eliminate a major source of error in the comet assay.

open access: yesFrontiers in Genetics, 2015
In the alkaline comet assay, cells are embedded in agarose, lysed, and then subjected to further processing including electrophoresis at high pH (>13). We observed very large variations of mean comet tail lengths of cell samples from the same population ...
Gunnar Brunborg
doaj   +1 more source

Comparative Evaluation of Genotoxicity of Captan in Amphibian Larvae (Xenopus laevis and Pleurodeles waltl) Using the Comet Assay and the Micronucleus Test [PDF]

open access: yes, 2006
Captan (N-trichloromethylthio-4-cyclohexene-1,2-dicarboximide) is a fungicide used to inhibit the growth of many types of fungi on plants used as foodstuffs.
Gauthier, Laury   +8 more
core   +1 more source

The Comet Assay: Tails of the (Un)expected. Use of the comet assay in pharmaceutical development.

open access: yesFrontiers in Genetics, 2015
In genotoxicity testing of pharmaceuticals the rodent alkaline comet assay is being increasingly used as a second in vivo assay in addition to the in vivo micronucleus assay to mitigate in vitro positive results as recommended by regulatory guidance.
Bas-jan Van Der Leede
doaj   +1 more source

Thermal model of water and CO activity of Comet C/1995 O1 (Hale-Bopp) [PDF]

open access: yes, 2011
An investigation of the activity of Comet C/1995 O1 (Hale-Bopp) with a thermophysical nucleus model that does not rely on the existence of amorphous ice is presented.
H.U. Keller   +8 more
core   +1 more source

The spectrin cytoskeleton is crucial for adherent and invasive bacterial pathogenesis. [PDF]

open access: yesPLoS ONE, 2011
Various enteric bacterial pathogens target the host cell cytoskeletal machinery as a crucial event in their pathogenesis. Despite thorough studies detailing strategies microbes use to exploit these components of the host cell, the role of the spectrin ...
Tyson Ruetz   +2 more
doaj   +1 more source

The Earth and Comets' Tails [PDF]

open access: yesScientific American, 1910
IN spite of the unreserved predictions of astronomers, the earth did not pass through the tail of Halley's comet on May 18–19, nor subsequently. The tail as seen in the morning sky, previous to the transit of the comet across the sun's disc, appeared like a long and straight beam of light stretching from the horizon to Aquila.
openaire   +3 more sources

Predictions of the solar wind interaction with Comet Grigg-Skjellerup [PDF]

open access: yes, 1992
The planned encounter of the Giotto spacecraft with comet Grigg-Skjellerup on 10th July 1992 promises to extend our knowledge of the solar wind interaction with comets substantially.
Johnstone, AD   +2 more
core  

Single Cell Analysis of Human RAD18-Dependent DNA Post-Replication Repair by Alkaline Bromodeoxyuridine Comet Assay [PDF]

open access: yes, 2013
Damage to DNA can block replication progression resulting in gaps in the newly synthesized DNA. Cells utilize a number of post-replication repair (PRR) mechanisms such as the RAD18 controlled translesion synthesis or template switching to overcome the ...
Himabindu Gali   +14 more
core   +2 more sources

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