Results 41 to 50 of about 106,793 (279)
Advanced Science, EarlyView.TNFRSF19 is an epigenetically silenced regulator of mitophagy in triple‐negative breast cancer. TNFRSF19 deficiency activates the TGFBR1–SMAD3–PINK1 axis to promote mitophagy and confer doxorubicin resistance, whereas decitabine‐mediated restoration of TNFRSF19 suppresses mitophagy and enhances doxorubicin sensitivity, revealing a targetable epigenetic–
Shiyang Liu +7 more
wiley +1 more source
Advanced Science, EarlyView.Mesenchymal GSCs preferentially uptake palmitic acid, thereby promoting ZDHHC12‐mediated LDHA palmitoylation. This modification enhances LDHA enzymatic activity, drives glycolytic reprogramming, and facilitates exosomal LDHA‐mediated TAM regulation.
Zijie Gao +20 more
wiley +1 more source
Hubble Space Telescope Observations of the Interstellar Interloper 3I/ATLAS
The Astrophysical Journal LettersWe present high-angular-resolution observations of the third known interstellar interloper, 3I/ATLAS, from the Hubble Space Telescope. The object is clearly active at 3.8 au preperihelion, showing dust emitted from the hot, Sun-facing side of the nucleus
David Jewitt +4 more
doaj +1 more source
Effect of age on the presence of comet tails at high altitude
, 2019 Extravascular lung water (EVLW) increases in healthy adults upon exposure to high altitude, likely due to increased pulmonary vascular resistance (PVR).
Coffman, KE +4 more
core +1 more source
Advanced Science, EarlyView.A recycling approach of spent lithium‐ion batteries is developed using brewing wastewater as the leaching agent and an engineering microbial consortium as the biocatalyst. Shewanella oneidensis reduces spent LiNixCoyMn1‐x‐yO2 cathodes via extracellular electron transfer, while Bacillus subtilis removes residual ethanol to eliminate inhibition.
Baocai Zhang +14 more
wiley +1 more source
Form and motion of cometary tails.
, 1976 This work deals with the geometrical problems inherent in the observation of cometary tails, and with attempts at explanation of their forms. Following the introduction, a review of the geometrical aspects of tail observation is presented in Chapter 2 ...
D. R. L. Jones (7702661)
core +3 more sources
Interstellar Object 3I/ATLAS Observed from Mars by China’s Tianwen-1 Spacecraft
The Astrophysical Journal LettersChina’s Tianwen-1 Mars orbiter successfully imaged the third interstellar object, 3I/ATLAS, during its close encounter with Mars using the onboard HiRIC CMOS camera. This is China’s first deep-space observation of an astronomical object.
Xin Ren +22 more
doaj +1 more source
Identification of Shigella flexneri IcsA residues affecting interaction with N-WASP, and evidence for IcsA-IcsA co-operative interaction. [PDF]
PLoS ONE, 2013 The Shigella flexneri IcsA (VirG) protein is a polarly distributed outer membrane protein that is a fundamental virulence factor which interacts with neural Wiskott-Aldrich syndrome protein (N-WASP). The activated N-WASP then activates the Arp2/3 complex
Min Yan Teh, Renato Morona
doaj +1 more source
Advanced Science, EarlyView.DDX21 suppresses MK2 activation by directly inhibiting Thr334 phosphorylation in a p38‐independent manner, thereby impairing DNA damage response. Clinically, patients with well‐differentiated tumors exhibiting high DDX21 expression are more likely to benefit from adjuvant radiotherapy, whereas those with low DDX21 levels are predisposed to ...
Tianru Yang +8 more
wiley +1 more source