Results 101 to 110 of about 2,393,076 (337)

Smart City Development with Urban Transfer Learning

, 2018
Nowadays, the smart city development levels of different cities are still unbalanced. For a large number of cities which just started development, the governments will face a critical cold-start problem: 'how to develop a new smart city service with ...
Guo, Bin, Wang, Leye, Yang, Qiang
core   +2 more sources

Calcium‐sensing receptor induces the apoptosis of chondrocytes in cooperation with phosphate transporter

FEBS Open Bio, EarlyView.
Excess Ca2+ ions activate the Calcium‐Sensing Receptor (CaSR), which subsequently drives the uptake of excess inorganic phosphate (Pi) via the Pi transporter (Pit−1) in chondrocytes. This mechanism causes a toxic increase in intracellular Pi concentration, ultimately leading to chondrocyte apoptosis and pathological mineralization. Excess extracellular
Sachie Nakatani, Hiroya Ueda, Ayumi Kawata, Yuki Sato, Kotomi Inomata, Hiroshi Mano, Masahiro Wada, Kenji Kobata   +7 more
wiley   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

FEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq, Nestor G. Casillas‐Vega, Alma Gomez‐Loredo, Xristo Zarate   +3 more
wiley   +1 more source

Quantum response of weakly chaotic systems

, 2010
Chaotic systems, that have a small Lyapunov exponent, do not obey the common random matrix theory predictions within a wide "weak quantum chaos" regime.
A. Stotland, Austin E. J., Backer A., Barnett A., Cohen D., D. Cohen, Degli Esposti M., L. M. Pecora, Lenz F., Prosen T., Ram-Mohan R., Robbins J. M., Stotland A., Stotland A., Wilkinson M., Wilkinson M., Wilkinson M.   +16 more
core   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Sex-Specific Associations between Prenatal Exposure to Di(2-ethylhexyl) Phthalate, Epigenetic Age Acceleration, and Susceptibility to Early Childhood Upper Respiratory Infections

Epigenomes
Di(2-ethylhexyl) phthalate (DEHP) is a common plasticizer that can affect immune system development and susceptibility to infection. Aging processes (measured as epigenetic age acceleration (EAA)) may mediate the immune-related effects of prenatal ...
Sarah M. Merrill, Nicole Letourneau, Gerald F. Giesbrecht, Karlie Edwards, Julia L. MacIsaac, Jonathan W. Martin, Amy M. MacDonald, David W. Kinniburgh, Michael S. Kobor, Deborah Dewey, Gillian England-Mason, The APrON Study Team   +11 more
doaj   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

Physics of galactic colliders: high speed satellites in LCDM vs MONDian cosmology

, 2009
The statistics of high speed satellite galaxies, as reported in the recent literature, can be a powerful diagnosis of the depth of the potential well of the host halo, and hence discriminate between competing gravitational theories.
Alexander Knebe, Bradač, Claudio Llinares, Dupke, Famaey, Hayashi, HongSheng Zhao, Jee, Jee, Jee, Knollmann, Komatsu, Madau, Mahdavi, Markevitch, Perets, Sanders, Will, Wu, Zhao, Zhao, Zhao, Zhao   +22 more
core   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

First-order thermal correction to the quadratic response tensor and rate for second harmonic plasma emission

, 2010
Three-wave interactions in plasmas are described, in the framework of kinetic theory, by the quadratic response tensor (QRT). The cold-plasma QRT is a common approximation for interactions between three fast waves.
B. Layden, D. J. Percival, Dulk G. A., Ginzburg V. L., Gorbunov L. M., Iver H. Cairns, Melrose D. B., P. A. Robinson, Sagdeev R. Z., Wild J. P., Zlotnik E. Y.   +10 more
core   +1 more source