Results 71 to 80 of about 2,393,076 (337)
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Behavioral Sciences, 2012 Previous research has shown that both experimentally induced upper respiratory tract illnesses (URTIs) and naturally occurring URTIs influence mood and performance.
Andrew P. Smith
doaj +1 more source
A Compact Thermal Heat Switch for Cryogenic Space Applications Operating near 100 K
, 2013 A thermal heat switch has been developed intended for cryogenic space applications operating around 100 K. The switch was designed to separate two pulse tube cold heads that cool a common focal plane array. Two cold heads are used for redundancy reasons,
Dietrich, Marc +2 more
core +1 more source
Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
Identification of medicinal plants effective on common cold: An ethnobotanical study of Shiraz, South Iran [PDF]
, 2016 Common cold is a very prevalent disease with cough, rhinorrhea, stuffy nose, and sore throat as the most common symptoms. Other symptoms include myalgia, fatigue, headache, and dyspepsia.
Asadi-Samani, Majid. +6 more
core
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Children, 2020 Background: Due to the frequency and severity of cold symptoms in children, and the risk of associated complications, effective treatments are urgently needed.
Ramon Weishaupt +5 more
doaj +1 more source
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
A Serious Adverse Effect of Pseudoephedrine Used For Common Cold Treatment : Ventricular Arrhythmia
Çukurova Üniversitesi Tıp Fakültesi Dergisi, 2013 Common cold is one of the frequently seen disease in childhood. Pseudoephedrine hydrochloride (PEH) is a sympathomimetic drug which is widely used for treatment of common cold as a decongestant on children.
Cenk Aypak +3 more
doaj