Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Nonpartisan Education ReviewThis paper examines the cognitive and curricular problems of Common Core elementary mathematics. Through analysis of Big Ideas Math and related instructional practices, it argues that, visual representations are employed excessively and without ...
Qianruo Shen
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Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Identifying common core outcome domains from core outcome sets of musculoskeletal conditions: protocol for a systematic review. [PDF]
Syst Rev, 2022 Sabet TS +7 more
europepmc +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
On the importance of the assessment and conceptualization of Agreeableness: A commentary on "Agreeableness and the common core of dark traits are functionally different constructs". [PDF]
J Res Pers, 2021 Vize CE, Lynam DR.
europepmc +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Review of Final Draft Core Standards [PDF]
Nonpartisan Education Review, 2013 What follows are my comments on the nal draft of the CCSSI Core Mathematics Standards. There are a number of standards including, but not limited to 1-OA(6), 2-OA(2), 2-NBT(5), 3-OA(7), 3-NBT(2), 4-OA(4), 4-OA(6), 4-NF(1), 4-NF(2), 5-OA(3), 8-G(2), 8-G(4)
R. James Milgram
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Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Current Issues in Education, 2014 In this article, a case study is presented of an urban first grade teachers perceptions of teaching English language arts (ELA) within a district-mandated scripted curriculum.
Susan A Sturm
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