Results 121 to 130 of about 8,033,499 (212)

Assessment in a Common Core Era: Revolutionary or Evolutionary?

Journal of Mathematics Education at Teachers College, 2012
In conjunction with the adoption and subsequent implementation of the Common Core State Standards for Mathematics (CCSSM), state-led consortia are developing next-generation assessments aligned to the CCSSM. This paper discusses the progress and plans of
Allen M. Dimacali
doaj  

Nicotiana tabacum seed endophytic communities share a common core structure and genotype-specific signatures in diverging cultivars. [PDF]

Comput Struct Biotechnol J, 2020
Chen X, Krug L, Yang H, Li H, Yang M, Berg G, Cernava T.   +6 more
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

The Organization Named Achieve: Cradle of Common Core Cronyism

Nonpartisan Education Review, 2018
no ...
Richard P. Phelps
doaj  

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

R. James Milgram on the Common Core in Indiana

Nonpartisan Education Review, 2017
Extended comments: "Testimony About Issues-With-Core Math Standards" [pdf] Testimony before the Indiana General Assembly, August 7, 2013 [pdf] Program: "The Changing Role of Education Conference at Notre Dame"
R. James Milgram
doaj  

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Agreement among common core temperature indices in defining critical environmental limits for human thermoregulation: a secondary analysis. [PDF]

Am J Physiol Regul Integr Comp Physiol
Leach OK, Meade RD, van den Bogaard T, O'Connor FK, Daanen HAM, Kenney WL, Kenny GP.   +6 more
europepmc   +1 more source