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Exploring Monogenic, Polygenic, and Epigenetic Models of Common Variable Immunodeficiency. [PDF]

open access: yesHum Mutat
Ranjbarnejad T   +6 more
europepmc   +1 more source

Common Variable Immunodeficiency

open access: yesThe Indian Journal of Pediatrics, 2016
Common variable immunodeficiency (CVID) is the most common primary immunodeficiency of young adolescents and adults which also affects the children. The disease remains largely under-diagnosed in India and Southeast Asian countries. Although in majority of cases it is sporadic, disease may be inherited in a autosomal recessive pattern and rarely, in ...
Biman, Saikia, Sudhir, Gupta
openaire   +3 more sources

Autoimmunity in Common Variable Immunodeficiency

open access: yesJournal of Clinical Immunology, 2008
Autoimmunity has been increasingly recognized as a major issue in patients with common variable immunodeficiency (CVID), the most common symptomatic primary immunodeficiency in adulthood. Different authors report high prevalences of autoimmune diseases in CVID, and several mechanisms have been proposed to explain this apparent paradox.
Susana, Lopes-da-Silva   +1 more
openaire   +3 more sources

Common variable immunodeficiency

Current Allergy and Asthma Reports, 2001
Common variable immunodeficiency (CVID) is a common primary immnodeficiency disease, the hallmark of which is hypogammaglobulinemia. Due to the lack of antibodies, patients usually have recurrent bacterial infections, but there are a number of other puzzling manifestations, including inflammatory conditions, autoimmune disease, and the development of ...
  +6 more sources

Common variable immunodeficiency: a review

Clinical and Experimental Medicine, 2004
Common variable immunodeficiency (CVID) is the commonest symptomatic primary antibody deficiency syndrome. The predominant manifestation is hypogammaglobulinemia. CVID is characterized by recurrent bacterial infections, especially of the upper and lower respiratory airways, and is also associated with an increased incidence of autoimmune and neoplastic
M, Di Renzo, A L, Pasqui, A, Auteri
openaire   +2 more sources

Common variable immunodeficiency in children

Current Opinion in Pediatrics, 2007
Common variable immunodeficiency is the most common primary immunodeficiency that needs medical attention. Symptoms may occur at any time, with two major peaks of onset at 5-10 and 20-30 years. We present the different clinical phenotypes of common variable immunodeficiency, review recent genetic findings and point to current treatment strategies.Five ...
Glocker, Erik-Oliver   +2 more
openaire   +3 more sources

Hepatitis in common variable immunodeficiency

Human Pathology, 2009
Common variable immunodeficiency is an important form of primary immunodeficiency disease. The most recognized histologic manifestation of common variable immunodeficiency is a paucity of plasma cells in gut biopsies. However, chronic inflammation can affect other organs including the liver.
Jason A, Daniels   +4 more
openaire   +2 more sources

Common variable immunodeficiency in a horse

Journal of the American Veterinary Medical Association, 2002
A 12-year-old Quarter Horse mare that was nonresponsive to medical treatment was evaluated for chronic respiratory disease and hepatobiliary disease. Serum immunoglobulin concentrations were measured by use of radial immunodiffusion that revealed trace to nondetectable concentrations of IgG, IgG(T), IgM, and IgA.
M Julia B F, Flaminio   +3 more
openaire   +2 more sources

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