Early-onset primary antibody deficiency resembling common variable immunodeficiency challenges the diagnosis of Wiedeman-Steiner and Roifman syndromes [PDF]
Syndromic primary immunodeficiencies are rare genetic disorders that affect both the immune system and other organ systems. More often, the immune defect is not the major clinical problem and is sometimes only recognized after a diagnosis has been made ...
Bogaert, Delfien +13 more
core +2 more sources
Unexpectedly High Prevalence of Common Variable Immunodeficiency in Finland [PDF]
Background: Common variable immunodeficiency (CVID) is the most common primary immunodeficiency. Prevalence varies greatly between countries and studies. Most diagnostic criteria include hypogammaglobulinemia and impaired vaccine response.
Aalto, Arja H. +13 more
core +1 more source
Common variable immunodeficiency disorder: a clinical case
Primary immunodeficiency is a rare congenital pathology associated with failure of immune system, manifested by disturbances of its functions. These defects lead to increased susceptibility of patients to various infectious agents, as well as the ...
E. A. Sobko +7 more
doaj +1 more source
Gastric cancer is the leading cause of death in Italian adult patients with common variable immunodeficiency [PDF]
An increased prevalence of malignant lymphoma and of gastric cancer has been observed in large cohorts of patients with common variable immunodeficiency (CVID), the most frequently symptomatic primary immunodeficiency. Surveillance strategies for cancers
Agostini, Carlo +11 more
core +3 more sources
Common variable immunodeficiency
We describe a patient with common variable immunodeficiency who three times presented an anaphylactic reaction after intravenous immunoglobulin administration. These reactions were attributed to the total absence of IgG 2, 3 and 4.
L R, de Almeida Barry, W C N, Forte
openaire +2 more sources
Enhanced formation of giant cells in common variable immunodeficiency: Relation to granulomatous disease. [PDF]
Peripheral monocytes from patients with common variable immunodeficiency (CVID) had on average a 2 fold greater tendency to form giant cells in medium without additional cytokines. Giant cell formation was faster and 3 to 5 fold higher in most CVID cells
Ardeniz +57 more
core +1 more source
British Lung Foundation/United Kingdom primary immunodeficiency network consensus statement on the definition, diagnosis, and management of granulomatous-lymphocytic interstitial lung disease in common variable immunodeficiency disorders [PDF]
A proportion of people living with common variable immunodeficiency disorders develop granulomatous-lymphocytic interstitial lung disease (GLILD). We aimed to develop a consensus statement on the definition, diagnosis, and management of GLILD.
Avery, Gerard R. +34 more
core +5 more sources
Immunologic alterations in common variable immunodeficiency
Common variable immunodeficiency (IDCV) is the largest group of symptomatic primary immune deficiencies; it is characterized by hypogammaglobulinemia, poor response to vaccines and increased susceptibility to infections.
Laura Berrón-Ruiz
doaj +1 more source
Posner-Schlossman Syndrome in Common Variable Immunodeficiency
Introduction. Posner-Schlossman syndrome (PSS) is a rare glaucomatocyclitic crisis with clinical features including recurrent episodes of unilateral elevated intraocular pressure.
Madiha Huq +3 more
doaj +1 more source
Primary vs. Secondary Antibody Deficiency: Clinical Features and Infection Outcomes of Immunoglobulin Replacement [PDF]
Secondary antibody deficiency can occur as a result of haematological malignancies or certain medications, but not much is known about the clinical and immunological features of this group of patients as a whole. Here we describe a cohort of 167 patients
AA Bousfiha +55 more
core +3 more sources

