Results 51 to 60 of about 4,530 (166)

Prevalence of gastrointestinal disorders in adults with common variable immunodeficiency at Specialty Hospital Dr. Bernardo Sepulveda

Revista Alergia México, 2015
Background: The common variable immunodeficiency (CVID) shows a variable incidence, from 1:15,000 to 1:117,000, whitout gender predominance. The incidence of gastrointestinal manifestations in these patients ranges from 20-60%, and these may be the first
Elda Victoria Rodríguez-Negrete, Arturo Mayoral-Zavala, Karen Alicia Rodríguez-Mireles, Oscar Edmundo Díaz de León-Salazar, Oscar Hernández-Mondragón, Luz María Gómez-Jiménez, R Moreno-Alcántar, Baldomero González-Virla   +7 more
doaj   +1 more source

Common variable immunodeficiency: familial inheritance and autoimmune manifestations in two siblings

The Turkish Journal of Pediatrics, 2010
Common variable immunodeficiency (CVID) is an immunodeficiency syndrome characterized by generalized defective antibody production and recurrent sinopulmonary bacterial infections.
Neslihan Edeer-Karaca, Nesrin Gülez, Güzide Aksu, Necil Kütükcüler   +3 more
doaj  

Revealing disease subtypes and heterogeneity in common variable immunodeficiency through transcriptomic analysis

Scientific Reports
Common Variable Immunodeficiency (CVID) is a primary immunodeficiency characterized by reduced levels of specific immunoglobulins, resulting in frequent infections, autoimmune disorders, increased cancer risk, and diminished antibody production despite ...
Mohammad Reza Zabihi, Zahra Moradi, Nima Safari, Zahra Salehi, Kaveh Kavousi   +4 more
doaj   +1 more source

Major approaches in early diagnostics of common variable immunodeficiency in adults in Moscow [v1; ref status: indexed, http://f1000r.es/UdeLt3]

F1000Research, 2012
Common variable immunodeficiency (CVID) is a primary immunological disease characterized predominantly by hypogammaglobulinemia. The main clinical manifestations are severe recurrent infections that often lead to structural damage of affected organs. The
Alexander V Karaulov, Irina V Sidorenko, Anna S Kapustina   +2 more
doaj   +1 more source

Immunophenotypical alterations in a subset of patients with common variable immunodeficiency (CVID)

Clinical and Experimental Immunology, 1992
SUMMARYWe investigated the expression of surface molecules on lymphocytes from 20 patients with CVID and 40 healthy subjects. Lymphocytes were analysed by dual colour flow cytometry. We identified a subset of patients (8 of 20) characterized by low CD4/CD8 ratio (< 1·1), expansion of T cells co-expressing the activation marker HLA-DR and ...
E, Baumert, G, Wolff-Vorbeck, M, Schlesier, H H, Peter   +3 more
openaire   +3 more sources

Bridging Rare to Common Diseases: Precision Medicine and the Transforming Landscape of Pediatric Allergy and Immunology

Pediatric Allergy and Immunology, Volume 37, Issue 6, June 2026.
This graphical abstract demonstrates a “rare‐to‐common” translational pipeline. Insights from rare monogenic conditions reveal key mechanisms of immune dysregulation. This knowledge informs the understanding of polygenic common allergic diseases, which share overlapping pathogenic pathways.
Riccardo Castagnoli, Martina Votto, Ivan Taietti, Maria Isabel Delgado‐Dolset, Rubén Fernández‐Santamaría, Martha Jimenez Freites, Mattia Giovannini, Mark Kačar, Aspasia Karavelia, Janice Layhadi, Urszula Radzikowska, Cezmi A. Akdis, Mubeccel Akdis, Marketa Bloomfield, Francesco Cinetto, Antoine Deschildre, Jonathan Hourihane, Susanne Lau, Antonio Nieto‐Garcia, Ismail Ogulur, Liam O'Mahony, Mohamed Shamji, Milena Sokolowska, Maria Jose Torres, Sophia Tsabouri, Philippe Eigenmann, on behalf of the EAACI‐Clemens von Pirquet Foundation   +26 more
wiley   +1 more source

Equine models in translational medicine: A comparative approach to human health

Animal Models and Experimental Medicine, Volume 9, Issue 5, Page 898-913, May 2026.
This diagram summarizes and contrasts rodent and equine models, outlining their strengths, limitations, and applications. Horses offer naturally occurring diseases, genetic and physiological similarities to humans, and suitability for longitudinal and clinical‐scale studies.
Shayan Boozarjomehri Amnieh, Katarzyna Ropka‐Molik   +1 more
wiley   +1 more source

Identification of a Novel De Novo Heterozygous SEC61A1 Variant in a Patient With Severe Congenital Neutropenia

Molecular Genetics &Genomic Medicine, Volume 14, Issue 5, May 2026.
Severe congenital neutropenia can be caused by rare SEC61A1 variants. We report a child with SCN showing granulocytic maturation arrest and abnormal immunophenotype, carrying a novel de novo SEC61A1 p.Trp379Arg variant, expanding the phenotypic and genetic spectrum of SEC61A1‐associated SCN.
Zixuan Wang, Hui Jing, Yuhan Chen, Ling Zhong, Jiyun Yang   +4 more
wiley   +1 more source

Double‐Blind Placebo Challenge Confirmation of Diphenhydramine Allergy

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Diphenhydramine, a first‐generation H1–antihistamine commonly used for allergic symptom relief and infusion premedication, rarely causes true systemic hypersensitivity. When suspected reactions are mild and subjective—particularly in anxious patients—objective confirmation is essential.
Ruchi Patel, Aleena Mahmood, Eugenio Capitle   +2 more
wiley   +1 more source

Common variable immunodeficiency and isosporiasis: first report case

Revista da Sociedade Brasileira de Medicina Tropical, 2012
We report a severe case of diarrhea in a 62-year-old female HIV-negative patient from whom Giardia lamblia and Isospora belli were isolated. Because unusual and opportunistic infections should be considered as criteria for further analysis of ...
Gisele Barbosa e Silva, Karla Pereira Fernandes, Gesmar Rodrigues Silva Segundo   +2 more
doaj   +1 more source