Results 71 to 80 of about 7,183,098 (196)

When to consider an inborn error of immunity: clues for physicians

Internal Medicine Journal, Volume 56, Issue 9, Page 1488-1499, September 2026.
Abstract The term inborn errors of immunity (IEIs) refers to the rapidly expanding group of genetic disorders causing dysregulation of the immune system. With improved genetic testing in recent years, the number of defined IEIs and their range of phenotypic presentations has grown vastly, with more than 550 IEIs now described.
Meera Thangarajah, Lucinda J. Berglund
wiley   +1 more source

Psoriasis in a cohort of patients with common variable immunodeficiency

, 2019
Common variable immunodeficiency (CVID) is the most common symptomatic primary immunodeficiency in adults. CVID is characterized by reduced serum levels of IgG, IgA, and/or IgM, recurrent bacterial infections, autoimmune and inflammatory diseases and ...
Pecoraro, A, CRESCENZI, LUDOVICA, Spadaro, G, Villani, A, Balato, N, Megna, M, Balato, A   +6 more
core   +1 more source

Common variable immunodeficiency and isosporiasis: first report case

Revista da Sociedade Brasileira de Medicina Tropical, 2012
We report a severe case of diarrhea in a 62-year-old female HIV-negative patient from whom Giardia lamblia and Isospora belli were isolated. Because unusual and opportunistic infections should be considered as criteria for further analysis of ...
Gisele Barbosa e Silva, Karla Pereira Fernandes, Gesmar Rodrigues Silva Segundo   +2 more
doaj   +1 more source

BAFF and APRIL Receptors in B Cell Immunity and Autoimmunity

Immunological Reviews, Volume 342, Issue 1, September 2026.
ABSTRACT BAFF and APRIL are TNF superfamily proteins that bind to BAFFR, TACI and BCMA, members of the TNF receptor superfamily. These proteins have both unique and overlapping roles in B cell development and survival and are major therapeutic targets for antibody‐ and B‐cell‐driven pathologies.
Daisy H. Luff, Edina Schweighoffer, Victor L. J. Tybulewicz   +2 more
wiley   +1 more source

The Developmental and Functional Implications of Age‐Associated B Cells (ABCs) Across Tissue Microenvironments

Immunological Reviews, Volume 341, Issue 1, August 2026.
ABSTRACT Age‐associated B cells (ABCs) are a dynamic B cell subset whose identity, development, and function are fundamentally shaped by the tissue microenvironments in which they reside. Primarily defined by expression of CD11c and T‐bet, ABCs arise across diverse contexts, including aging, infection, autoimmunity, and cancer, yet exhibit striking ...
Rebecca L. Francis, Jason S. Weinstein
wiley   +1 more source

Neurologic Complications of Common Variable Immunodeficiency [PDF]

, 2016
Common variable immunodeficiency is a rare disorder of immunity associated with a myriad of clinical manifestations including recurrent infections, autoimmunity, and malignancy.
Nguyen, Jenna Thuc-Uyen, Gundling, Katherine, Green, Ari, DeRisi, Joseph L, Wilson, Michael R   +4 more
core   +1 more source

Common variable immunodeficiency (CVID) presenting with malabsorption due to giardiasis

The Turkish Journal of Gastroenterology, 2005
Common variable immunodeficiency is characterized with B-cell and T-cell dysfunction and hypogammaglobulinemia. Recurrent bacterial infections, such as otitis media, chronic sinusitis and recurrent pneumonia due to diminished immunoglobulin (Ig) levels and impaired antibody production are frequently observed in common variable immunodeficiency.
Kevser ONBAŞI, Fulya GÜNŞAR, Aytül Z. SİN, Ömür ARDENİZ, Ali KOKULUDAĞ, Filiz SEBİK   +5 more
doaj   +3 more sources

Identification of microorganisms related to chronic rhinosinusitis in adult patients with variable common immunodeficiency

Revista Alergia México, 2016
Background: The prevalence of chronic rhinosinusitis in adult patients with common variable immunodeficiency (CVID) is 52%. The patients with CVID show higher incidence of chronic rhinosinusitis, which is an inflammatory disease that affects the lining ...
Gabriela Angulo-Pérez, Eulalio Vivar-Acevedo, Diana Andrea Herrera-Sánchez   +2 more
doaj   +1 more source

Behind the scenes: Primary immunodeficiencies in pediatric eosinophilic gastrointestinal diseases

Pediatric Allergy and Immunology, Volume 37, Issue 8, August 2026.
Using a multifaceted approach combining medical history, JMF warning signs, physical examination, and comprehensive immunological evaluation, we identified a considerable frequency of PIDs among pediatric patients with EGID, predominantly antibody deficiencies. JMF warning signs were present in only a minority of patients.
Kubra Baskin, H. Ilbilge Ertoy Karagol, Kenan Cetin, Zeynep Cavdar, Sumeyra Aktepe, Ilknur Atalay Can, Hakan Ozturk, Odul Egritas Gurkan, Sinan Sari, Buket Dalgic, Arzu Bakirtas   +10 more
wiley   +1 more source

Piecing together the subtle clues of common variable immunodeficiency

, 2023
Common variable immunodeficiency (CVID) is a primary immunodeficiency disorder that results in decreased immunity and increased infection risk. This multisystem disorder often presents as recurrent, prolonged respiratory tract infections.
Kochanoff, Kimberly DeVore
core   +1 more source