Results 61 to 70 of about 7,183,098 (196)

Immunophenotypical alterations in a subset of patients with common variable immunodeficiency (CVID)

Clinical and Experimental Immunology, 1992
SUMMARYWe investigated the expression of surface molecules on lymphocytes from 20 patients with CVID and 40 healthy subjects. Lymphocytes were analysed by dual colour flow cytometry. We identified a subset of patients (8 of 20) characterized by low CD4/CD8 ratio (< 1·1), expansion of T cells co-expressing the activation marker HLA-DR and ...
E, Baumert, G, Wolff-Vorbeck, M, Schlesier, H H, Peter   +3 more
openaire   +3 more sources

The association between inborn errors of immunity and Hodgkin lymphoma—A register‐based case–control study in Sweden

British Journal of Haematology, Volume 209, Issue 4, Page 1629-1637, October 2026.
Summary Immune dysfunction is implicated in the aetiology of Hodgkin lymphoma (HL), but the association between inborn errors of immunity (IEI) and HL remains poorly understood. We conducted a retrospective, register‐based case–control study in Sweden over five decades to investigate the relationship between IEI and HL. Individuals diagnosed with HL in
Agnes Winsa, Ingemar Lagerlöf, Fredrik Ellin, Mats Fredriksson, Åsa Nilsdotter‐Augustinsson, Marcus Bendtsen, Jörg Cammenga, Sofia Nyström   +7 more
wiley   +1 more source

Pathogenesis of immune thrombocytopenia in common variable immunodeficiency [PDF]

, 2020
Immune Thrombocitopenic Purpura (ITP) is an autoimmune disease characterized by antibody-mediated platelet destruction and variable reduced platelet production.
Jadav G., Lunardi, Claudio., Beri R., Puccetti A., Beri, Ruggero, Dima F., Bason C., Dima, Francesco, Bason, Caterina, Dolcino, Marzia, Argentino, Giuseppe, Jadav, Gnaneshwer, Argentino G., Veneri, Dino, Puccetti, Antonio, Tinazzi E., Dolcino M., Osti, Nicola, Osti N., Lunardi C., Veneri D., Tinazzi, Elisa   +21 more
core   +1 more source

Revealing disease subtypes and heterogeneity in common variable immunodeficiency through transcriptomic analysis

Scientific Reports
Common Variable Immunodeficiency (CVID) is a primary immunodeficiency characterized by reduced levels of specific immunoglobulins, resulting in frequent infections, autoimmune disorders, increased cancer risk, and diminished antibody production despite ...
Mohammad Reza Zabihi, Zahra Moradi, Nima Safari, Zahra Salehi, Kaveh Kavousi   +4 more
doaj   +1 more source

Prevalence of gastrointestinal disorders in adults with common variable immunodeficiency at Specialty Hospital Dr. Bernardo Sepulveda

Revista Alergia México, 2015
Background: The common variable immunodeficiency (CVID) shows a variable incidence, from 1:15,000 to 1:117,000, whitout gender predominance. The incidence of gastrointestinal manifestations in these patients ranges from 20-60%, and these may be the first
Elda Victoria Rodríguez-Negrete, Arturo Mayoral-Zavala, Karen Alicia Rodríguez-Mireles, Oscar Edmundo Díaz de León-Salazar, Oscar Hernández-Mondragón, Luz María Gómez-Jiménez, R Moreno-Alcántar, Baldomero González-Virla   +7 more
doaj   +1 more source

Liver transplantation in patients with common variable immunodeficiency: a report of two cases

, 2014
Common variable immunodeficiency (CVID) is the most common primary immunodeficiency disease and is a heterogeneous group of antibody deficiency syndromes characterized by hypogammaglobulinemia, recurrent bacterial infections, and frequent autoimmune ...
Mocchegiani, Federico, Vivarelli M., Nicolini D, Nicolini, Daniele, Svegliati Baroni, Gianluca, Vincenzi P, Montalti, Roberto, Vincenzi, Paolo, Vivarelli, Marco, Montalti R   +9 more
core   +1 more source

Management of Refractory and Difficult‐To‐Treat Inflammatory Bowel Disease: An Expert Opinion Review

JCC Plus, Volume 1, Issue 5, September 2026.
This expert opinion offers a practical framework for refractory and difficult‐to‐treat IBD: confirm inflammation objectively, distinguish pharmacologic from structural and functional disease, and then escalate. Across ten clinical questions, the evidence is often limited to case series, and the resulting statements are identified as expert opinion ...
Filiz Akyuz, Oguz Kagan Bakkaloglu, Nalan Gulsen Unal, Ismail Hakki Kalkan, Mehmet Arhan, Ibrahim Hatemi, Taylan Kav, Murat Toruner, Hale Akpinar, Ahmet Tezel, Aykut Ferhat Celik   +10 more
wiley   +1 more source

Major approaches in early diagnostics of common variable immunodeficiency in adults in Moscow [v1; ref status: indexed, http://f1000r.es/UdeLt3]

F1000Research, 2012
Common variable immunodeficiency (CVID) is a primary immunological disease characterized predominantly by hypogammaglobulinemia. The main clinical manifestations are severe recurrent infections that often lead to structural damage of affected organs. The
Alexander V Karaulov, Irina V Sidorenko, Anna S Kapustina   +2 more
doaj   +1 more source

Phenotype‐specific immune profiles and outcomes in childhood autoimmune neutropenia: A 20‐year cohort study

British Journal of Haematology, Volume 209, Issue 3, Page 1158-1165, September 2026.
Summary Childhood autoimmune neutropenia (AIN) encompasses heterogeneous entities; phenotype‐specific immunological profiles and their relationship to infection outcomes remain incompletely defined. To characterise clinical, immunological and long‐term outcomes across distinct phenotypes of childhood AIN.
Ioanna Saougou, Chrysoula Kosmeri, Nikolaos Chaliasos, Irene Mavroudi, Charalampos Pontikoglou, Alexandros Makis   +5 more
wiley   +1 more source

The 2025 ATS/ERS update of the international multidisciplinary classification of the interstitial pneumonias: implications for the pathologist

Histopathology, Volume 89, Issue 3, Page 403-425, September 2026.
This review highlights changes relevant to pathologists in the updated multidisciplinary classification of interstitial pneumonias. Changes include expansion beyond idiopathic disease, subclassification as interstitial (fibrotic vs non‐fibrotic) and alveolar filling disorders, expansion to include additional patterns (e.g.
Andrew G Nicholson, Wendy A. Cooper, Aurelie Fabre, William Travis, Lida P. Hariri, Ayodeji Adegunsoye, Sara Piciucchi, Christopher J Ryerson   +7 more
wiley   +1 more source