Results 71 to 80 of about 339,166 (359)

Reframing non-communicable diseases [PDF]

The Lancet Global Health, 2017
​Proposer de travailler sur les maladies chroniques non-infectieuses comme "maladies socialement transmises" ("socially transmitted conditions") prolonge un lieu commun partage depuis plusieurs decennies en epidemiologie sur le caractere plurifactoriel de ces maladies. Cela ne doit pas empecher de penser que les maladies infectieuses doivent aussi etre
Cavalin, Catherine, Lescoat, Alain
openaire   +7 more sources

Peripheral blood leukocyte signatures as biomarkers in relapsed ovarian cancer patients receiving combined anti‐CD73/anti‐PD‐L1 immunotherapy in arm A of the NSGO‐OV‐UMB1/ENGOT‐OV30 trial

Molecular Oncology, EarlyView.
Using mass cytometry, we analyzed serial blood samples from patients with relapsed epithelial ovarian cancer (EOC) treated with oleclumab–durvalumab combination immunotherapy in the NSGO‐OV‐UMB1/ENGOT‐OV30 trial. Our analysis identified potential predictive, monitoring, and response biomarkers detectable through liquid biopsy. These findings facilitate
Luka Tandaric, Annika Auranen, Katrin Kleinmanns, René DePont Christensen, Liv Cecilie Vestrheim Thomsen, Cara Ellen Wogsland, Emmet McCormack, Johanna Mäenpää, Kristine Madsen, Karen Stampe Petersson, Mansoor Raza Mirza, Line Bjørge   +11 more
wiley   +1 more source

The Post-2015 Development Agenda: Keeping Our Focus On the Worst Off [PDF]

, 2015
Non-communicable diseases now account for the majority of the global burden of disease and an international campaign has emerged to raise their priority on the post-2015 development agenda. We argue, to the contrary, that there remain
Sharp, D.
core   +1 more source

Stroma gene signature predicts responsiveness to chemotherapy in pancreatic ductal adenocarcinoma patient‐derived xenograft models

Molecular Oncology, EarlyView.
Pancreatic ductal adenocarcinoma patient‐derived xenografts (PDAC‐PDXs) engrafted orthotopically in the pancreas of immunodeficient mice retain the main genetic and histopathological characteristics of the original human tumors. A 294 stroma gene signature differentiates between PDAC‐PDXs that are responsive to gemcitabine plus nab‐paclitaxel versus ...
Alessia Anastasia, Laura Formenti, Paola Ostano, Lucia Minoli, Andrea Resovi, Lavinia Morosi, Claudia Fioravanti, Edoardo Micotti, Cristina Matteo, Eugenio Scanziani, Giovanna Chiorino, Raffaella Giavazzi, Carmen Ghilardi, Dorina Belotti   +13 more
wiley   +1 more source

The association of inflammatory markers in early pregnancy with the development of gestational diabetes: Qazvin maternal and neonatal metabolic study (QMNS)

BMC Pregnancy and Childbirth
Background This study investigates the association of blood cell components and blood cell-derived inflammatory indices in early pregnancy with the development of gestational diabetes mellitus (GDM).
Sima Hashemipour, Seyedeh Sareh Kalantarian, Hamidreza Panahi, Sara Esmaeili Kelishomi, Amirabbas Ghasemi, Sarah Mirzaeei Chopani, Sepideh Kolaji, Milad Badri, Arefeh Ghobadi, Seyyed Mohammad Reza Hadizadeh Khairkhahan, Fatemeh Lalooha, Farideh Movahed, Mahnaz Abbasi, Khadijeh Elmizadeh   +13 more
doaj   +1 more source

Mortality from non-communicable diseases in South Africa, 1997-2009 [PDF]

, 2014
There are estimates of the magnitude of non-communicable disease deaths for less developed countries but little is known about the dynamics in Africa. The continent is undergoing unprecedented growth of the elderly population.
Lalthapersad-Pillay, Pinky, Udjo, Eric O
core   +2 more sources

International law and communicable diseases

Bulletin of the World Health Organization, 2002
Historically, international law has played a key role in global communicable disease surveillance. Throughout the nineteenth century, international law played a dominant role in harmonizing the inconsistent national quarantine regulations of European ...
Aginam Obijiofor
doaj  

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

Emergence of protective behaviour under different risk perceptions to disease spreading [PDF]

arXiv, 2021
The behaviour of individuals is a main actor in the control of the spread of a communicable disease and, in turn, the spread of an infectious disease can trigger behavioural changes in a population. Here, we study the emergence of the individuals protective behaviours in response to the spread of a disease by considering two different social attitudes ...
arxiv  

Identification of inhibitors of the Salmonella FraB deglycase, a drug target

FEBS Open Bio, EarlyView.
A high‐throughput screen was used to identify inhibitors of Salmonella FraB, a drug target. Characterization of top hits (identified after an additional counter screen) revealed that some triazolidines, thiadiazolidines, and triazolothiadiazoles are mixed‐type inhibitors of FraB.
Jamison D. Law, Yuan Gao, Sravya Kovvali, Pankajavalli Thirugnanasambantham, Vicki H. Wysocki, Brian M. M. Ahmer, Venkat Gopalan   +6 more
wiley   +1 more source