Results 51 to 60 of about 1,358,497 (293)

Compact objects from gravitational collapse: an analytical toy model [PDF]

, 2015
We develop here a procedure to obtain regular static configurations as resulting from dynamical gravitational collapse of a massive matter cloud in general relativity. Under certain general physical assumptions for the collapsing cloud, we find the class
Joshi, Pankaj S., Malafarina, Daniele
core   +4 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

SHIP: a computational framework for simulating and validating novel technologies in hardware spiking neural networks

Frontiers in Neuroscience
Investigations in the field of spiking neural networks (SNNs) encompass diverse, yet overlapping, scientific disciplines. Examples range from purely neuroscientific investigations, researches on computational aspects of neuroscience, or applicative ...
Emanuele Gemo, Sabina Spiga, Stefano Brivio   +2 more
doaj   +1 more source

Compact vortex in a generalized Born-Infeld model

, 2011
We study vortexlike solutions in a generalized Born-Infeld model. The model is driven by two distinct parameters, one which deals with the Born-Infeld term, and the other, which controls the presence of high-order power term in the covariant derivative ...
Bazeia, D., da Hora, E., Rubiera-Garcia, D.   +2 more
core   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

Materials Selection Principles for Designing Electro‐Thermal Neurons

Advanced Electronic Materials
Artificial neurons exhibiting volatile threshold switching and action potential‐like oscillations are crucial for brain‐inspired computing. While Complimentary Metal‐Oxide‐Semiconductor (CMOS)‐based strategies require hundreds of transistors to simulate ...
Fatme Jardali, Jenny L. Chong, Yeonju Yu, R. Stanley Williams, Suhas Kumar, Patrick J. Shamberger, Timothy D. Brown   +6 more
doaj   +1 more source

A Constrained Standard Model from a Compact Extra Dimension

, 2001
A SU(3) \times SU(2) \times U(1) supersymmetric theory is constructed with a TeV sized extra dimension compactified on the orbifold S^1/(Z_2 \times Z_2'). The compactification breaks supersymmetry leaving a set of zero modes which correspond precisely to
A. Delgado, A. Delgado, A. Pomarol, A. Strumia, A.H. Chamseddine, B. de Wit, B. de Wit, B. de Wit, C.D. Carone, D.J. Castano, D.Z. Freedman, E. Accomando, E. Witten, H. Goldberg, I. Antoniadis, I. Antoniadis, I. Antoniadis, I. Antoniadis, I. Antoniadis, I. Antoniadis, I. Antoniadis, I. Antoniadis, J. Ellis, J. Scherk, J. Scherk, K. Benakli, K. Inoue, K. Inoue, K. Inoue, K.R. Dienes, K.R. Dienes, L. Alvarez-Gaume, L. Dixon, L. Dixon, L. Ibanez, L.E. Ibanez, L.J. Hall, Lawrence J. Hall, M. Gell-Mann, M. Masip, M. Veltman, N. Arkani-Hamed, N. Arkani-Hamed, N. Sakai, P. Breitenlohner, P. Breitenlohner, P. Fayet, P. Fayet, P. Nath, P. Nath, P. Nath, R. Casalbuoni, Riccardo Barbieri, S. Dimopoulos, S. Dimopoulos, T. Yanagida, T.G. Rizzo, W.J. Marciano, Yasunori Nomura, Z. Chacko   +59 more
core   +1 more source

Lattice Regularization of the Chiral Schwinger Model [PDF]

, 1996
We analyze the chiral Schwinger model on an infinite lattice using the continuum definition of the fermion determinant and a linear interpolation of the lattice gauge fields.
't Hooft, Abdalla, Alvarez-Gaumé, Banerjee, Christof Gattringer, Flume, Fröhlich, Fröhlich, Gattringer, Gattringer, Girotti, Girotti, Göckeler, Göckeler, Göckeler, Hernandez, Jackiw, Karsten, Linhares, Nielsen, Nielsen, Niemi, Osterwalder, Osterwalder, Osterwalder, Rajaraman, Schwinger, Seiler, Shamir, Simon, Wilson   +30 more
core   +2 more sources