Results 41 to 50 of about 475,850 (295)

Gravitational Waves from Compact Objects Accreting onto Active Galactic Nuclei [PDF]

open access: yes, 2006
We consider a model in which massive stars form in a self-gravitating accretion disk around an active galactic nucleus. These stars may evolve and collapse to form compact objects on a time scale shorter than the accretion time, thus producing an ...
Buonanno, Alessandra   +2 more
core   +4 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Casimir forces between arbitrary compact objects

open access: yes, 2007
We develop an exact method for computing the Casimir energy between arbitrary compact objects, either dielectrics or perfect conductors. The energy is obtained as an interaction between multipoles, generated by quantum current fluctuations.
E. M. Lifshitz   +8 more
core   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

open access: yesFEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli   +9 more
wiley   +1 more source

Do Central Compact Objects have Carbon Atmospheres?

open access: yesThe Astrophysical Journal, 2023
Only three of the dozen central compact objects (CCOs) in supernova remnants (SNRs) show thermal X-ray pulsations due to nonuniform surface temperature (hot spots). The absence of X-ray pulsations from several unpulsed CCOs has motivated suggestions that
J. A. J. Alford, J. P. Halpern
doaj   +1 more source

Superburst: surface phenomenon of compact objects

open access: yes, 2005
We suggest that superbursts from some low mass X-ray binaries may be due to breaking and re-formation of diquark pairs, on the surface of realistic strange stars.
Bhaduri   +8 more
core   +1 more source

Identifying Compact Symmetric Objects in the Southern Sky [PDF]

open access: yes, 2003
We present results of multifrequency polarimetric VLBA observations of 20 compact radio sources. The observations represent the northern and southern extensions of a large survey undertaken to identify Compact Symmetric Objects (CSOs) Observed in the ...
A. B. Peck   +5 more
core   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

First Observations of SN 1604 (Kepler’s Supernova)

open access: yesUniverse, 2021
A supernova close enough to the Earth is a spectacular event: it can appear as a “new star” as luminous as Venus, or even more, visible for several days.
Alessandro de Angelis, Selenia Broccio
doaj   +1 more source

Testing strong gravity with gravitational waves and Love numbers [PDF]

open access: yes, 2017
The LIGO observation of GW150914 has inaugurated the gravitational-wave astronomy era and the possibility of testing gravity in extreme regimes. While distorted black holes are the most convincing sources of gravitational waves, similar signals might be ...
Cardoso, V.   +3 more
core   +1 more source

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