Results 11 to 20 of about 449,093 (327)

Comparative genome assembly [PDF]

open access: yesBriefings in Bioinformatics, 2004
One of the most complex and computationally intensive tasks of genome sequence analysis is genome assembly. Even today, few centres have the resources, in both software and hardware, to assemble a genome from the thousands or millions of individual sequences generated in a whole-genome shotgun sequencing project.
Mihai, Pop   +3 more
openaire   +3 more sources

Plasmodium comparative genomics [PDF]

open access: yesBriefings in Functional Genomics, 2019
Malaria is a serious infectious disease caused by unicellular eukaryotic parasites of the genus Plasmodium. Today more than 200 species exist [1], and whole-genome sequence data is available for around 22 species [2]. At least five different Plasmodium species can infect humans, of which Plasmodium falciparum is the major cause of morbidity and ...
Ranford-Cartwright, Lisa   +1 more
openaire   +3 more sources

Ebolaviruscomparative genomics [PDF]

open access: yesFEMS Microbiology Reviews, 2015
(Uploaded by Plazi for the Bat Literature Project) The 2014 Ebola outbreak in West Africa is the largest documented for this virus. To examine the dynamics of this genome, we compare more than 100 currently available ebolavirus genomes to each other and to other viral genomes.
Jun, Se Ran   +14 more
openaire   +4 more sources

Comparative genomics of Shiga toxin encoding bacteriophages [PDF]

open access: yes, 2012
Background Stx bacteriophages are responsible for driving the dissemination of Stx toxin genes (stx) across their bacterial host range. Lysogens carrying Stx phages can cause severe, lifethreatening disease and Stx toxin is an integral virulence factor.
Allison, Heather   +6 more
core   +2 more sources

Rational Design of Short Locked Nucleic Acid-Modified 2′-O-Methyl Antisense Oligonucleotides for Efficient Exon-Skipping In Vitro

open access: yesMolecular Therapy: Nucleic Acids, 2017
Locked nucleic acid is a prominent nucleic acid analog with unprecedented target binding affinity to cDNA and RNA oligonucleotides and shows remarkable stability against nuclease degradation.
Bao T. Le   +4 more
doaj   +1 more source

Complete mitochondrial genome of Mekong fighting fish, Betta smaragdina (Teleostei: Osphronemidae)

open access: yesMitochondrial DNA. Part B. Resources, 2021
Mekong fighting fish (Betta smaragdina) are found in Northeast Thailand. A complete mitochondrial genome (mitogenome) of B. smaragdina was assembled and annotated.
Nararat Laopichienpong   +14 more
doaj   +1 more source

Comparative Genomics of 9 Novel Paenibacillus Larvae Bacteriophages [PDF]

open access: yes, 2016
American Foulbrood Disease, caused by the bacterium Paenibacillus larvae, is one of the most destructive diseases of the honeybee, Apis mellifera. Our group recently published the sequences of 9 new phages with the ability to infect and lyse P.
Amy, Penny S.   +4 more
core   +2 more sources

Comparative genomic hybridization

open access: yesAnnual Review of Genomics and Human Genetics, 2005
▪ Abstract  Altering DNA copy number is one of the many ways that gene expression and function may be modified. Some variations are found among normal individuals ( 14 , 35 , 103 ), others occur in the course of normal processes in some species ( 33 ), and still others participate in causing various disease states.
Daniel, Pinkel, Donna G, Albertson
openaire   +2 more sources

Mitochondrial genome of bronze-winged jacana (Metopidius indicus, Latham 1790)

open access: yesMitochondrial DNA. Part B. Resources, 2021
We reported the mitochondrial genome (mitogenome) of bronze-winged jacana (Metopidius indicus, Latham ). The circular mitogenome was 17,208 base pairs (bp) in length, containing 13 protein-coding genes, two rRNAs, 22 tRNAs, and a non-coding control ...
Jitmat Thintip   +11 more
doaj   +1 more source

Alvira : comparative genomics of viral strains [PDF]

open access: yes, 2007
The Alvira tool is a general purpose multiple sequence alignment viewer with a special emphasis on the comparative analysis of viral genomes. This new tool has been devised specifically to address the problem of the simultaneous analysis of a large ...
Brodie   +10 more
core   +4 more sources

Home - About - Disclaimer - Privacy