Results 21 to 30 of about 449,093 (327)

RNA-Seq and iTRAQ reveal multiple pathways involved in storage root formation and development in sweet potato (Ipomoea batatas L.)

BMC Plant Biology, 2019
Background Sweet potato (Ipomoea batatas L.) is the sixth most important food crop in the world. The formation and development of storage roots in sweet potato is a highly complicated and genetically programmed process. However, the underlying mechanisms
Tingting Dong, Mingku Zhu, Jiawen Yu, Rongpeng Han, Cheng Tang, Tao Xu, Jingran Liu, Zongyun Li   +7 more
doaj   +1 more source

Novel Chemically-modified DNAzyme targeting Integrin alpha-4 RNA transcript as a potential molecule to reduce inflammation in multiple sclerosis

Scientific Reports, 2017
Integrin alpha-4 (ITGA4) is a validated therapeutic target for multiple sclerosis (MS) and Natalizumab, an antibody targeting ITGA4 is currently approved for treating MS. However, there are severe side effects related to this therapy.
Madhuri Chakravarthy, May T. Aung-Htut, Bao T. Le, Rakesh N. Veedu   +3 more
doaj   +1 more source

Antisense Oligonucleotide-Mediated Terminal Intron Retention of the SMN2 Transcript

Molecular Therapy: Nucleic Acids, 2018
The severe childhood disease spinal muscular atrophy (SMA) arises from the homozygous loss of the survival motor neuron 1 gene (SMN1). A homologous gene potentially encoding an identical protein, SMN2 can partially compensate for the loss of SMN1 ...
Loren L. Flynn, Chalermchai Mitrpant, Ianthe L. Pitout, Sue Fletcher, Steve D. Wilton   +4 more
doaj   +1 more source

Performance and Scalability of Discriminative Metrics for Comparative Gene Identification in 12 Drosophila Genomes [PDF]

, 2010
Comparative genomics of multiple related species is a powerful methodology for the discovery of functional genomic elements, and its power should increase with the number of species compared.
Deoras, Ameya N., Guigó, Roderic, Kellis, Manolis, Lin, Michael, Rasmussen, Matthew D.   +4 more
core   +1 more source

Comparative Genomics

PLoS Biology, 2003
Comparing the genomes of two different species allow the exploration of a host of intriguing evolutionary and genetic ...
openaire   +5 more sources

Integrated Analysis of Metabolome and Transcriptome Reveals the Difference in Flavonoid Biosynthesis between the Red- and White-Sarcocarp Pomelo Fruits

Metabolites, 2022
Flavonoids are bioactive secondary metabolites that play multiple roles in plants. However, studies on the flavonoid accumulation of the pomelo fruit are rare.
Chenxu Zhao, Jiajia Wang, Yuxia Li, Lei Zhang, Ghazala Nawaz, Shaoyuan Wu, Tao Xu   +6 more
doaj   +1 more source

Dynamics of GATA1 binding and expression response in a GATA1-induced erythroid differentiation system

Genomics Data, 2015
During the maturation phase of mammalian erythroid differentiation, highly proliferative cells committed to the erythroid lineage undergo dramatic changes in morphology and function to produce circulating, enucleated erythrocytes.
Deepti Jain, Tejaswini Mishra, Belinda M. Giardine, Cheryl A. Keller, Christapher S. Morrissey, Susan Magargee, Christine M. Dorman, Maria Long, Mitchell J. Weiss, Ross C. Hardison   +9 more
doaj   +1 more source

Comparative genomic data of the Avian Phylogenomics Projects [PDF]

, 2014
The evolutionary relationships of modern birds are among the most challenging to understand in systematic biology and have been debated for centuries.

core   +1 more source

Whole genome sequencing of canids reveals genomic regions under selection and variants influencing morphology

Nature Communications, 2019
Being man’s best friend, dogs have been bred and selected for certain morphologic traits and breed-associated behaviours. Here, Plassais et al. analyse 722 canine whole genome sequences including modern breeds, wild canids and village dogs by GWAS and ...
Jocelyn Plassais, Jaemin Kim, Brian W. Davis, Danielle M. Karyadi, Andrew N. Hogan, Alex C. Harris, Brennan Decker, Heidi G. Parker, Elaine A. Ostrander   +8 more
doaj   +1 more source

Next-generation sequencing yields complete mitochondrial genome assembly of peaceful betta fish, Betta imbellis (Teleostei: Osphronemidae)

Mitochondrial DNA. Part B. Resources, 2020
The complete mitochondrial genome (mitogenome) of the peaceful betta (Betta imbellis) was obtained using next-generation sequencing. The sample of B. imbellis was collected from its native habitat in Southern Thailand.
Syed Farhan Ahmad, Nararat Laopichienpong, Worapong Singchat, Aorarat Suntronpong, Tavun Pongsanarm, Thitipong Panthum, Nattakan Ariyaraphong, Jakaphan Bulan, Tanawat Pansrikaew, Kornsuang Jangtarwan, Navapong Subpayakom, Sahabhop Dokkaew, Narongrit Muangmai, Prateep Duengkae, Kornsorn Srikulnath   +14 more
doaj   +1 more source