Results 31 to 40 of about 449,093 (327)

Probabilistic Clustering of Sequences: Inferring new bacterial regulons by comparative genomics [PDF]

, 2002
Genome wide comparisons between enteric bacteria yield large sets of conserved putative regulatory sites on a gene by gene basis that need to be clustered into regulons. Using the assumption that regulatory sites can be represented as samples from weight
Bailey, Bausch, Begley, Berg, Cheek, E. D. Siggia, E. van Nimwegen, Gelfand, Jacobson, Jennings, Lawrence, M. Zavolan, McCue, McGuire, N. Rajewsky, Peekhaus, Peekhaus, Robison, Salgado, Sengupta, Stormo, van Nimwegen   +21 more
core   +2 more sources

Reconstruction of proto-vertebrate, proto-cyclostome and proto-gnathostome genomes provides new insights into early vertebrate evolution

Nature Communications, 2021
Early vertebrate genomes were shaped by multiple whole-genome duplication (WGD) events of debated timings. Here the authors’ reconstruction of ancestral genomes using the probabilistic macrosynteny model supports a WGD shared by all vertebrates and a ...
Yoichiro Nakatani, Prashant Shingate, Vydianathan Ravi, Nisha E. Pillai, Aravind Prasad, Aoife McLysaght, Byrappa Venkatesh   +6 more
doaj   +1 more source

Comparative Genomics of a Parthenogenesis-Inducing Wolbachia Symbiont. [PDF]

, 2016
Wolbachia is an intracellular symbiont of invertebrates responsible for inducing a wide variety of phenotypes in its host. These host-Wolbachia relationships span the continuum from reproductive parasitism to obligate mutualism, and provide a unique ...
Lindsey, Amelia RI, Richards, Stephen, Stouthamer, Richard, Werren, John H   +3 more
core   +3 more sources

Comparative genomics of Chlamydomonas

The Plant Cell, 2020
Abstract Despite its role as a reference organism in the plant sciences, the green alga Chlamydomonas reinhardtii entirely lacks genomic resources from closely related species. We present highly contiguous and well-annotated genome assemblies for three unicellular C.
Rory J Craig, Ahmed R Hasan, Rob W Ness, Peter D Keightley   +3 more
openaire   +3 more sources

PhyloCSF: a comparative genomics method to distinguish protein-coding and non-coding regions [PDF]

, 2010
As high-throughput transcriptome sequencing provides evidence for novel transcripts in many species, there is a renewed need for accurate methods to classify small genomic regions as protein-coding or non-coding.
Arvestad, Blanchette, Brent, Butler, Clark, Goldman, Guttman, Guttman, Holmes, I. Jungreis, Kellis, Lin, M. F. Lin, M. Kellis, Ota, Ozsolak, Stark, Whelan, Yang   +18 more
core   +4 more sources

Eukfinder: a pipeline to retrieve microbial eukaryote genome sequences from metagenomic data

mBio
Whole-genome shotgun (WGS) metagenomic sequencing of microbial communities enables the discovery of the functions, physiologies, and evolutionary histories of prokaryotic and eukaryotic microbes.
Dandan Zhao, Dayana E. Salas-Leiva, Shelby K. Williams, Katherine A. Dunn, Jason D. Shao, Andrew J. Roger   +5 more
doaj   +1 more source

Synthesis of a Morpholino Nucleic Acid (MNA)-Uridine Phosphoramidite, and Exon Skipping Using MNA/2′-O-Methyl Mixmer Antisense Oligonucleotide

Molecules, 2016
In this study, we synthesised a morpholino nucleoside-uridine (MNA-U) phosphoramidite and evaluated the potential of a MNA-modified antisense oligonucleotide (AO) sequences to induce exon 23 skipping in mdx mouse myotubes in vitro towards extending the ...
Suxiang Chen, Bao T. Le, Kamal Rahimizadeh, Khalil Shaikh, Narinder Mohal, Rakesh N. Veedu   +5 more
doaj   +1 more source

Exogenous Melatonin Attenuates Post-Harvest Decay by Increasing Antioxidant Activity in Wax Apple (Syzygium samarangense)

Frontiers in Plant Science, 2020
Wax apple is one of the most popular tropical fruit but undergoes serious post-harvest decay during storage, transportation and marketing. Melatonin (MT) plays important roles in plant growth, development and stress responses.
Yao Chen, Yanjie Zhang, Ghazala Nawaz, Chenxu Zhao, Yuxia Li, Tingting Dong, Mingku Zhu, Ximeng Du, Lei Zhang, Zongyun Li, Tao Xu   +10 more
doaj   +1 more source

Genomic Inference of the Metabolism and Evolution of the Archaeal Phylum Aigarchaeota [PDF]

, 2018
Microbes of the phylum Aigarchaeota are widely distributed in geothermal environments, but their physiological and ecological roles are poorly understood.
Castelle, Cindy J., Hedlund, Brian P., Hua, Zheng-Shuang, Knight, Rob, Li, Wen-Jun, Li, Yu-Xian, Liu, Lan, Qi, Yan-Ling, Qu, Yan-Ni, Rao, Yang-Zhi, Shu, Wen-Sheng, Tian, Ye, Yin, Yi-Rui, Zhou, En-Min, Zhu, Qiyun   +14 more
core   +3 more sources

Integrating coalescent species delimitation with analysis of host specificity reveals extensive cryptic diversity despite minimal mitochondrial divergence in the malaria parasite genus Leucocytozoon

BMC Evolutionary Biology, 2018
Background Coalescent methods that use multi-locus sequence data are powerful tools for identifying putatively reproductively isolated lineages, though this approach has rarely been used for the study of microbial groups that are likely to harbor many ...
Spencer C. Galen, Renato Nunes, Paul R. Sweet, Susan L. Perkins   +3 more
doaj   +1 more source