Results 31 to 40 of about 2,755,876 (359)

Comparative Genomics

PLoS Biology, 2003
Comparing the genomes of two different species allow the exploration of a host of intriguing evolutionary and genetic ...
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Novel Chemically-modified DNAzyme targeting Integrin alpha-4 RNA transcript as a potential molecule to reduce inflammation in multiple sclerosis

Scientific Reports, 2017
Integrin alpha-4 (ITGA4) is a validated therapeutic target for multiple sclerosis (MS) and Natalizumab, an antibody targeting ITGA4 is currently approved for treating MS. However, there are severe side effects related to this therapy.
Madhuri Chakravarthy, May T. Aung-Htut, Bao T. Le, Rakesh N. Veedu   +3 more
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RNA-Seq and iTRAQ reveal multiple pathways involved in storage root formation and development in sweet potato (Ipomoea batatas L.)

BMC Plant Biology, 2019
Background Sweet potato (Ipomoea batatas L.) is the sixth most important food crop in the world. The formation and development of storage roots in sweet potato is a highly complicated and genetically programmed process. However, the underlying mechanisms
Tingting Dong, Mingku Zhu, Jiawen Yu, Rongpeng Han, Cheng Tang, Tao Xu, Jingran Liu, Zongyun Li   +7 more
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Antisense Oligonucleotide-Mediated Terminal Intron Retention of the SMN2 Transcript

Molecular Therapy: Nucleic Acids, 2018
The severe childhood disease spinal muscular atrophy (SMA) arises from the homozygous loss of the survival motor neuron 1 gene (SMN1). A homologous gene potentially encoding an identical protein, SMN2 can partially compensate for the loss of SMN1 ...
Loren L. Flynn, Chalermchai Mitrpant, Ianthe L. Pitout, Sue Fletcher, Steve D. Wilton   +4 more
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Comparative genomics of microsporidia [PDF]

Folia Parasitologica, 2005
Microsporidia have been known for some time to possess among the smallest genomes of any eukaryote. There is now a completely sequenced microsporidian genome, as well as several other large-scale sequencing efforts, so the nature of these genomes is becoming apparent.
Bryony A. P. Williams, Joyce S. Law, Naomi M. Fast, Patrick J. Keeling, Claudio H. Slamovits   +4 more
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Integrated Analysis of Metabolome and Transcriptome Reveals the Difference in Flavonoid Biosynthesis between the Red- and White-Sarcocarp Pomelo Fruits

Metabolites, 2022
Flavonoids are bioactive secondary metabolites that play multiple roles in plants. However, studies on the flavonoid accumulation of the pomelo fruit are rare.
Chenxu Zhao, Jiajia Wang, Yuxia Li, Lei Zhang, Ghazala Nawaz, Shaoyuan Wu, Tao Xu   +6 more
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Comparative Genomics of Leuconostoc carnosum [PDF]

Frontiers in Microbiology, 2021
Leuconostoc carnosum is a known colonizer of meat-related food matrices. It reaches remarkably high loads during the shelf life in packaged meat products and plays a role in spoilage, although preservative effects have been proposed for some strains. In this study, the draft genomes of 17 strains of L.
Francesco Candeliere, Stefano Raimondi, Gloria Spampinato, Moon Yue Feng Tay, Moon Yue Feng Tay, Alberto Amaretti, Alberto Amaretti, Joergen Schlundt, Joergen Schlundt, Maddalena Rossi, Maddalena Rossi   +10 more
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Whole genome sequencing of canids reveals genomic regions under selection and variants influencing morphology

Nature Communications, 2019
Being man’s best friend, dogs have been bred and selected for certain morphologic traits and breed-associated behaviours. Here, Plassais et al. analyse 722 canine whole genome sequences including modern breeds, wild canids and village dogs by GWAS and ...
Jocelyn Plassais, Jaemin Kim, Brian W. Davis, Danielle M. Karyadi, Andrew N. Hogan, Alex C. Harris, Brennan Decker, Heidi G. Parker, Elaine A. Ostrander   +8 more
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Dynamics of GATA1 binding and expression response in a GATA1-induced erythroid differentiation system

Genomics Data, 2015
During the maturation phase of mammalian erythroid differentiation, highly proliferative cells committed to the erythroid lineage undergo dramatic changes in morphology and function to produce circulating, enucleated erythrocytes.
Deepti Jain, Tejaswini Mishra, Belinda M. Giardine, Cheryl A. Keller, Christapher S. Morrissey, Susan Magargee, Christine M. Dorman, Maria Long, Mitchell J. Weiss, Ross C. Hardison   +9 more
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Next-generation sequencing yields complete mitochondrial genome assembly of peaceful betta fish, Betta imbellis (Teleostei: Osphronemidae)

Mitochondrial DNA. Part B. Resources, 2020
The complete mitochondrial genome (mitogenome) of the peaceful betta (Betta imbellis) was obtained using next-generation sequencing. The sample of B. imbellis was collected from its native habitat in Southern Thailand.
Syed Farhan Ahmad, Nararat Laopichienpong, Worapong Singchat, Aorarat Suntronpong, Tavun Pongsanarm, Thitipong Panthum, Nattakan Ariyaraphong, Jakaphan Bulan, Tanawat Pansrikaew, Kornsuang Jangtarwan, Navapong Subpayakom, Sahabhop Dokkaew, Narongrit Muangmai, Prateep Duengkae, Kornsorn Srikulnath   +14 more
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